{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Hu Q"],"pubmed_abstract":["<h4>Backgrounds</h4>Osteoporosis is a prevalent bone disease. Previous research has indicated that various forms of exercise have different protective effects on bone health, yet there are limited studies on the impact of walking pace on bone mineral density (BMD) and skeletal health. This study aims to investigate the correlation between usual walking pace and osteoporosis, including related fractures, while considering potential interactions with genetic vulnerability.<h4>Methods</h4>Survey responses from 348,334 participants in the UK Biobank were analyzed, obtaining information on usual walking pace, BMD, osteoporosis incidence, and genetic vulnerability. Multiple linear regression, Cox proportional hazards regression models, and stratified analysis methods were employed. A weighted ge"],"journal":["Frontiers in endocrinology"],"pagination":["1635999"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12417151"],"repository":["biostudies-literature"],"pubmed_title":["Walking pace and its association with osteoporosis and pathological fractures: insights from UK biobank."],"pmcid":["PMC12417151"],"pubmed_authors":["Liu H","Duan R","Du Y","Ouyang Z","Hu Q","Yang D","Li L"],"additional_accession":[]},"is_claimable":false,"name":"Walking pace and its association with osteoporosis and pathological fractures: insights from UK biobank.","description":"<h4>Backgrounds</h4>Osteoporosis is a prevalent bone disease. Previous research has indicated that various forms of exercise have different protective effects on bone health, yet there are limited studies on the impact of walking pace on bone mineral density (BMD) and skeletal health. This study aims to investigate the correlation between usual walking pace and osteoporosis, including related fractures, while considering potential interactions with genetic vulnerability.<h4>Methods</h4>Survey responses from 348,334 participants in the UK Biobank were analyzed, obtaining information on usual walking pace, BMD, osteoporosis incidence, and genetic vulnerability. Multiple linear regression, Cox proportional hazards regression models, and stratified analysis methods were employed. A weighted ge","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-05-26T11:06:52.736Z","creation":"2026-05-24T03:07:05.735Z"},"accession":"S-EPMC12417151","cross_references":{"pubmed":["40933376"],"doi":["10.3389/fendo.2025.1635999"]}}