{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang Y"],"funding":["National Natural Science Foundation of China"],"pagination":["1081-1087"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12418542"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["109(9)"],"pubmed_abstract":["<h4>Aims</h4>Previous studies have suggested an association between retinal artery occlusion (RAO) and ischaemic stroke (IS), both associated with elevated inflammatory factors. However, the role of high-sensitivity C-reactive protein (hs-CRP) in the sequential onset of these two diseases is still unclear. Based on this evidence, we evaluated the association of hs-CRP with RAO and IS.<h4>Methods</h4>We examined hs-CRP from both the large multicentre cohort study UK Biobank and Chinese Retinal Artery Occlusion study. Cox proportional hazard models were used to study the association of hs-CRP with incident RAO and IS during the long-term follow-up in the UK Biobank. Logistic regression analysis was employed to assess the cross-sectional relationship between hs-CRP with RAO and IS in the Chin"],"journal":["The British journal of ophthalmology"],"pubmed_title":["High-sensitivity C-reactive protein and risk of retinal artery occlusion and ischaemic stroke: a cross-cohort study."],"pmcid":["PMC12418542"],"funding_grant_id":["82301205","82171075","82301260","82271125"],"pubmed_authors":["Zhang F","Zhu Z","Hu Y","Du Z","Wu G","Liang A","Yu H","Niu Y","Chen D","Fang Y","Zhang X","Shang X","Chen X","Hu L","Wang Y","Wu W"],"additional_accession":[]},"is_claimable":false,"name":"High-sensitivity C-reactive protein and risk of retinal artery occlusion and ischaemic stroke: a cross-cohort study.","description":"<h4>Aims</h4>Previous studies have suggested an association between retinal artery occlusion (RAO) and ischaemic stroke (IS), both associated with elevated inflammatory factors. However, the role of high-sensitivity C-reactive protein (hs-CRP) in the sequential onset of these two diseases is still unclear. Based on this evidence, we evaluated the association of hs-CRP with RAO and IS.<h4>Methods</h4>We examined hs-CRP from both the large multicentre cohort study UK Biobank and Chinese Retinal Artery Occlusion study. Cox proportional hazard models were used to study the association of hs-CRP with incident RAO and IS during the long-term follow-up in the UK Biobank. Logistic regression analysis was employed to assess the cross-sectional relationship between hs-CRP with RAO and IS in the Chin","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-06-02T00:23:29.494Z","creation":"2026-05-24T03:07:57.606Z"},"accession":"S-EPMC12418542","cross_references":{"pubmed":["39904581"],"doi":["10.1136/bjo-2023-325044"]}}