{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["123(5)"],"submitter":["Almeida J"],"funding":["European Commission","Biotechnology and Biological Sciences Research Council"],"pubmed_abstract":["Plastoglobuli (PG) are plant lipoprotein compartments, present in plastid organelles. They are involved in the formation and/or storage of lipophilic metabolites. FIBRILLINs (FBNs) are one of the main PG-associated proteins and are particularly abundant in carotenoid-enriched chromoplasts found in ripe fruits and flowers. To address the contribution of different FBNs, independently and in combination, to isoprenoid formation and sequestration, a multiplex gene editing approach was undertaken in tomato. This approach generated a suite of single and high-order fbn mutants that were shown to lack transcripts and respective protein products. The major PG-related FBNs in tomato chosen for this study are SlFBN1, SlFBN2a, SlFBN4 and SlFBN7a. When knocked out independently, functional redundancy w"],"journal":["The Plant journal : for cell and molecular biology"],"pagination":["e70447"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12419240"],"repository":["biostudies-literature"],"pubmed_title":["The FIBRILLIN multigene family in tomato, their roles in plastoglobuli structure and metabolism."],"pmcid":["PMC12419240"],"pubmed_authors":["Fraser PD","Drapal M","Enfissi EMA","Perez-Fons L","Almeida J","Liew K"],"additional_accession":[]},"is_claimable":false,"name":"The FIBRILLIN multigene family in tomato, their roles in plastoglobuli structure and metabolism.","description":"Plastoglobuli (PG) are plant lipoprotein compartments, present in plastid organelles. They are involved in the formation and/or storage of lipophilic metabolites. FIBRILLINs (FBNs) are one of the main PG-associated proteins and are particularly abundant in carotenoid-enriched chromoplasts found in ripe fruits and flowers. To address the contribution of different FBNs, independently and in combination, to isoprenoid formation and sequestration, a multiplex gene editing approach was undertaken in tomato. This approach generated a suite of single and high-order fbn mutants that were shown to lack transcripts and respective protein products. The major PG-related FBNs in tomato chosen for this study are SlFBN1, SlFBN2a, SlFBN4 and SlFBN7a. When knocked out independently, functional redundancy w","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-05-26T17:00:57Z","creation":"2026-05-24T03:07:49.449Z"},"accession":"S-EPMC12419240","cross_references":{"pubmed":["40924023"],"doi":["10.1111/tpj.70447"]}}