biostudies-literatureUnknown19(9)Smith DJ<h4>Background</h4>Chromoblastomycosis and phaeohyphomycotic abscesses are infections of the skin and subcutaneous tissues caused by dematiaceous fungi; more rarely, phaeohyphomycotic brain abscesses can occur. The epidemiology and clinical outcomes of chromoblastomycosis and phaeohyphomycotic abscesses are not well-understood in the United States.<h4>Methodology/ principal findings</h4>We used data from the Healthcare Cost and Utilization Project's National Inpatient Sample to obtain yearly national estimates of chromoblastomycosis and phaeohyphomycotic abscess-associated hospitalizations. We examined age group, sex, Census region, season of hospital admission, clinical form of chromoblastomycosis, and presence of selected concurrent conditions. An estimated 690 chromoblastomycosis and phPLoS neglected tropical diseasese0013499https://www.ebi.ac.uk/biostudies/studies/S-EPMC12419653biostudies-literatureChromoblastomycosis and phaeohyphomycotic abscess-associated hospitalizations, United States, 2016-2021.PMC12419653Lockhart SRSmith DJBenedict KRevankar SGfalseChromoblastomycosis and phaeohyphomycotic abscess-associated hospitalizations, United States, 2016-2021.<h4>Background</h4>Chromoblastomycosis and phaeohyphomycotic abscesses are infections of the skin and subcutaneous tissues caused by dematiaceous fungi; more rarely, phaeohyphomycotic brain abscesses can occur. The epidemiology and clinical outcomes of chromoblastomycosis and phaeohyphomycotic abscesses are not well-understood in the United States.<h4>Methodology/ principal findings</h4>We used data from the Healthcare Cost and Utilization Project's National Inpatient Sample to obtain yearly national estimates of chromoblastomycosis and phaeohyphomycotic abscess-associated hospitalizations. We examined age group, sex, Census region, season of hospital admission, clinical form of chromoblastomycosis, and presence of selected concurrent conditions. An estimated 690 chromoblastomycosis and ph2025-01-01T00:00:00Z2025 Sep2026-06-02T17:45:20.584Z2026-05-27T03:07:36.077ZS-EPMC124196534090677510.1371/journal.pntd.0013499