{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(9)"],"submitter":["Otsubo T"],"pubmed_abstract":["<h4>Background</h4>Atrial biopsy is technically challenging owing to the atria's thin walls and relatively thick endocardium. This study assessed the feasibility and safety of echocardiography-guided atrial biopsy in a consecutive cohort of 1,000 patients who underwent catheter ablation for atrial tachyarrhythmias or percutaneous left atrial (LA) appendage occlusion.<h4>Methods and results</h4>Atrial biopsy was performed at the limbus of the fossa ovalis through the femoral vein using a 5.5-Fr (n=233) or a 7.0-Fr (n=767) bioptome under intracardiac (n=963) or transesophageal (n=37) echocardiography guidance, alongside fluoroscopy. For histological analysis, 5 tissue samples were collected from the same site. Biopsy was successfully completed in 996 (99.6%) patients. Patients were divided b"],"journal":["Circulation reports"],"pagination":["764-773"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12419951"],"repository":["biostudies-literature"],"pubmed_title":["Feasibility and Safety of Atrial Biopsy　- Evidence From 1,000 Cases."],"pmcid":["PMC12419951"],"pubmed_authors":["Osako R","Otsubo T","Fukui A","Shinzato K","Aoki S","Nakashima K","Node K","Hirota K","Takahashi Y","Shichida S","Edayoshi M","Nishimura Y","Ito K","Sasano T","Tsuruta K","Kawano Y","Kawaguchi A","Yamaguchi T","Yokoi K","Takigawa M","Takahashi N","Shintani-Domoto Y","Nomura S","Miyazaki K"],"additional_accession":[]},"is_claimable":false,"name":"Feasibility and Safety of Atrial Biopsy　- Evidence From 1,000 Cases.","description":"<h4>Background</h4>Atrial biopsy is technically challenging owing to the atria's thin walls and relatively thick endocardium. This study assessed the feasibility and safety of echocardiography-guided atrial biopsy in a consecutive cohort of 1,000 patients who underwent catheter ablation for atrial tachyarrhythmias or percutaneous left atrial (LA) appendage occlusion.<h4>Methods and results</h4>Atrial biopsy was performed at the limbus of the fossa ovalis through the femoral vein using a 5.5-Fr (n=233) or a 7.0-Fr (n=767) bioptome under intracardiac (n=963) or transesophageal (n=37) echocardiography guidance, alongside fluoroscopy. For histological analysis, 5 tissue samples were collected from the same site. Biopsy was successfully completed in 996 (99.6%) patients. Patients were divided b","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-02T17:37:50.282Z","creation":"2026-04-18T03:11:54.129Z"},"accession":"S-EPMC12419951","cross_references":{"pubmed":["40933496"],"doi":["10.1253/circrep.CR-25-0101"]}}