{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["114(10)"],"submitter":["Martello E"],"pubmed_abstract":["<h4>Aim</h4>The aim of this review is to systematically summarise the evidence on the effectiveness of riboflavin (vitamin B2) or supplements containing riboflavin in preventing paediatric migraines.<h4>Methods</h4>This systematic review followed the Joanna Briggs Institute methodology and is reported to adhere to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched multiple electronic databases on 25 October 2023 to identify potentially relevant studies. Studies were screened, critically appraised and data extracted by two reviewers. Data underwent a narrative synthesis using vote counting based on direction of effect and was presented using harvest plots.<h4>Results</h4>Seventeen studies of varying quality were included in the review. Riboflavin "],"journal":["Acta paediatrica (Oslo, Norway : 1992)"],"pagination":["2443-2457"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12420874"],"repository":["biostudies-literature"],"pubmed_title":["Systematic Review Suggests Nutraceuticals Containing Vitamin B2 Could Provide an Alternative Treatment for Paediatric Migraines."],"pmcid":["PMC12420874"],"pubmed_authors":["Ikechukwu P","Seripenah P","Joseph T","Koboto D","Leonardi-Bee J","Stewart-Evans J","Dhungana S","Wilson E","Morling JR","Aiyelabegan F","Orr J","Martello E","Kinali M","Emery H"],"additional_accession":[]},"is_claimable":false,"name":"Systematic Review Suggests Nutraceuticals Containing Vitamin B2 Could Provide an Alternative Treatment for Paediatric Migraines.","description":"<h4>Aim</h4>The aim of this review is to systematically summarise the evidence on the effectiveness of riboflavin (vitamin B2) or supplements containing riboflavin in preventing paediatric migraines.<h4>Methods</h4>This systematic review followed the Joanna Briggs Institute methodology and is reported to adhere to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched multiple electronic databases on 25 October 2023 to identify potentially relevant studies. Studies were screened, critically appraised and data extracted by two reviewers. Data underwent a narrative synthesis using vote counting based on direction of effect and was presented using harvest plots.<h4>Results</h4>Seventeen studies of varying quality were included in the review. Riboflavin ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-02T20:19:20.462Z","creation":"2026-04-20T03:10:15.301Z"},"accession":"S-EPMC12420874","cross_references":{"pubmed":["40411246"],"doi":["10.1111/apa.70157"]}}