{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yang R"],"funding":["National Key Research and Development Program","National Natural Science Foundation of China","Capital's Funds for Health Improvement and Research of Beijing"],"pagination":["2685-2693"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12423017"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["42(8)"],"pubmed_abstract":["<h4>Purpose</h4>To investigate if trophectoderm (TE) biopsy on preimplantation genetic testing (PGT) increases the risk of obstetrical and infant outcomes after frozen single blastocyst transfer cycles.<h4>Methods</h4>This retrospective cohort study included all frozen single blastocyst transfer cycles conducted between January 2012 and December 2017 at Peking University Third Hospital. A total of 1492 patients in the PGT group and 600 patients in the non-PGT group were analyzed. The primary outcomes were clinical pregnancy rate, live birth rate, and early motor development milestones. Secondary outcomes included miscarriage, obstetric complications, and infant outcomes.<h4>Results</h4>The PGT group had younger parental ages and higher antral follicle counts, whereas the non-PGT group had "],"journal":["Journal of assisted reproduction and genetics"],"pubmed_title":["The obstetrical and infant outcomes of trophectoderm biopsy on preimplantation genetic testing embryos after frozen single embryo transfer cycles."],"pmcid":["PMC12423017"],"funding_grant_id":["82171632","2022YFC2702905","2021YFC2700605","2024-2-40911","2024YFC2706702"],"pubmed_authors":["Li J","Chen L","Liu P","Zhang N","Yang R","Tian T","Han Z","Li R","Wang Y","Wang J","Qiao J","Gao C"],"additional_accession":[]},"is_claimable":false,"name":"The obstetrical and infant outcomes of trophectoderm biopsy on preimplantation genetic testing embryos after frozen single embryo transfer cycles.","description":"<h4>Purpose</h4>To investigate if trophectoderm (TE) biopsy on preimplantation genetic testing (PGT) increases the risk of obstetrical and infant outcomes after frozen single blastocyst transfer cycles.<h4>Methods</h4>This retrospective cohort study included all frozen single blastocyst transfer cycles conducted between January 2012 and December 2017 at Peking University Third Hospital. A total of 1492 patients in the PGT group and 600 patients in the non-PGT group were analyzed. The primary outcomes were clinical pregnancy rate, live birth rate, and early motor development milestones. Secondary outcomes included miscarriage, obstetric complications, and infant outcomes.<h4>Results</h4>The PGT group had younger parental ages and higher antral follicle counts, whereas the non-PGT group had ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-06-01T23:29:33.761Z","creation":"2026-05-23T03:08:12.501Z"},"accession":"S-EPMC12423017","cross_references":{"pubmed":["40632424"],"doi":["10.1007/s10815-025-03512-7"]}}