{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sharma R"],"funding":["California Department of Fish and Game"],"pagination":["246"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12423146"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["138(10)"],"pubmed_abstract":["To breed for climate resilient crops, an understanding of the genetic and environmental factors influencing adaptation is critical. Barley provides a model species to study adaptation to climate change. Here we present a detailed analysis of genetic variation at a major photoperiod response locus and relate this to the domestication history and dispersal of barley. The PPD-H1 locus (a PSEUDO-RESPONSE REGULATOR 7) promotes flowering under long-day conditions, and a natural mutation at this locus resulted in a recessive, late-flowering ppd-H1 allele. This mutation proved beneficial in high-latitude environments such as Northern Europe, where it allows extended vegetative growth during long spring days. We infer the origin of the mutated late-flowering ppd-H1 allele by re-sequencing a large g"],"journal":["TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik"],"pubmed_title":["On the origin of the late-flowering ppd-H1 allele in barley."],"pmcid":["PMC12423146"],"funding_grant_id":["SPP1530"],"pubmed_authors":["Powell W","Coupland G","Sharma R","Shaaf S","Guo Y","Ceccarelli S","Neumann K","Baum M","Blake T","Grando S","Al-Yassin A","Castaneda-Alvarez NP","Kilian B","Mascher M","Pillen K","Weiss E","Civan P","Ozkan H","Mackay IJ","Graner A","David M","Hubner S"],"additional_accession":[]},"is_claimable":false,"name":"On the origin of the late-flowering ppd-H1 allele in barley.","description":"To breed for climate resilient crops, an understanding of the genetic and environmental factors influencing adaptation is critical. Barley provides a model species to study adaptation to climate change. Here we present a detailed analysis of genetic variation at a major photoperiod response locus and relate this to the domestication history and dispersal of barley. The PPD-H1 locus (a PSEUDO-RESPONSE REGULATOR 7) promotes flowering under long-day conditions, and a natural mutation at this locus resulted in a recessive, late-flowering ppd-H1 allele. This mutation proved beneficial in high-latitude environments such as Northern Europe, where it allows extended vegetative growth during long spring days. We infer the origin of the mutated late-flowering ppd-H1 allele by re-sequencing a large g","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-03T07:44:34.066Z","creation":"2026-04-26T03:09:49.905Z"},"accession":"S-EPMC12423146","cross_references":{"pubmed":["40931145"],"doi":["10.1007/s00122-025-04981-1"]}}