{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Schmidt R"],"funding":["German Federal Ministry of Education and Research"],"pagination":["1701-1709"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12423583"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["58(9)"],"pubmed_abstract":["<h4>Objective</h4>Cognitive-behavioral therapy (CBT) is the most well-established treatment for binge-eating disorder (BED), but the mechanisms of change remain poorly understood. This study investigated in CBT for BED the effects of overvaluation of shape and weight and dietary restraint on subsequent objective binge-eating episodes (OBEs).<h4>Method</h4>In a multicenter randomized-controlled trial, 84 patients diagnosed with full- or subsyndromal BED were offered 20 individual sessions of CBT over 4 months. Dynamic structural equation modeling (DSEM) was used to disentangle within- and between-patient associations of overvaluation of shape and weight, dietary restraint, and OBEs.<h4>Results</h4>Between the first and last week of therapy, there were significant reductions in overvaluation"],"journal":["The International journal of eating disorders"],"pubmed_title":["Mechanisms of Change in Cognitive-Behavioral Therapy for Adults With Binge-Eating Disorder: A Dynamic Structural Equation Modeling Approach."],"pmcid":["PMC12423583"],"funding_grant_id":["01GV0601","01EO1501"],"pubmed_authors":["de Zwaan M","Schmidt R","Schewe D","Friederich HC","Tuschen-Caffier B","Mayr A","Hilbert A","Herpertz S","Zipfel S"],"additional_accession":[]},"is_claimable":false,"name":"Mechanisms of Change in Cognitive-Behavioral Therapy for Adults With Binge-Eating Disorder: A Dynamic Structural Equation Modeling Approach.","description":"<h4>Objective</h4>Cognitive-behavioral therapy (CBT) is the most well-established treatment for binge-eating disorder (BED), but the mechanisms of change remain poorly understood. This study investigated in CBT for BED the effects of overvaluation of shape and weight and dietary restraint on subsequent objective binge-eating episodes (OBEs).<h4>Method</h4>In a multicenter randomized-controlled trial, 84 patients diagnosed with full- or subsyndromal BED were offered 20 individual sessions of CBT over 4 months. Dynamic structural equation modeling (DSEM) was used to disentangle within- and between-patient associations of overvaluation of shape and weight, dietary restraint, and OBEs.<h4>Results</h4>Between the first and last week of therapy, there were significant reductions in overvaluation","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-01T23:28:25.885Z","creation":"2026-05-23T03:08:06.65Z"},"accession":"S-EPMC12423583","cross_references":{"pubmed":["40396334"],"doi":["10.1002/eat.24469"]}}