biostudies-literatureUnknown24(9)Menezes MVA<h4>Background</h4>Hyaluronic acid (HA) fillers are a key treatment in the augmentation and rejuvenation of the lips. The novel Multi Vector (MV) Lip technique has been developed using specific injection vectors in geometric forms to shape the lips-allowing precise customization according to the needs of individual patients.<h4>Aims</h4>To describe the MV Lip technique and evaluate its safety and effectiveness in patients treated across five centers in Brazil.<h4>Methods</h4>This was a retrospective analysis of data from adult female subjects. Eligible patients were treated using the HA filler, VYC-17.5L, in multiple different zones of the lips and perioral area, based on predefined vectors filling geometric shapes.<h4>Results</h4>A total of 253 patients from a range of ethnic backgrounds Journal of cosmetic dermatologye70445https://www.ebi.ac.uk/biostudies/studies/S-EPMC12424118biostudies-literatureAesthetic Treatment of the Lips With Hyaluronic Acid Filler: The Multi Vector Lip Technique.PMC12424118de Aquino SBGMenezes MVAPenna FWPDezanetti CBGCury RSLfalseAesthetic Treatment of the Lips With Hyaluronic Acid Filler: The Multi Vector Lip Technique.<h4>Background</h4>Hyaluronic acid (HA) fillers are a key treatment in the augmentation and rejuvenation of the lips. The novel Multi Vector (MV) Lip technique has been developed using specific injection vectors in geometric forms to shape the lips-allowing precise customization according to the needs of individual patients.<h4>Aims</h4>To describe the MV Lip technique and evaluate its safety and effectiveness in patients treated across five centers in Brazil.<h4>Methods</h4>This was a retrospective analysis of data from adult female subjects. Eligible patients were treated using the HA filler, VYC-17.5L, in multiple different zones of the lips and perioral area, based on predefined vectors filling geometric shapes.<h4>Results</h4>A total of 253 patients from a range of ethnic backgrounds 2025-01-01T00:00:00Z2025 Sep2026-05-26T20:16:48.454Z2026-05-24T03:06:57.457ZS-EPMC124241184093193010.1111/jocd.70445