biostudies-literatureUnknown30(26)Feghaly JWe present a case of successful transfemoral transcatheter aortic valve replacement for a rare quadricuspid aortic valve with pure aortic regurgitation. Procedural challenges included identifying the annular plane, determining the appropriate deployment view, annular sizing, the absence of annular calcium, and the lack of a dedicated transcatheter device for pure aortic regurgitation.JACC. Case reports104879https://www.ebi.ac.uk/biostudies/studies/S-EPMC12426643biostudies-literatureTransfemoral TAVR in a Quadricuspid Aortic Valve With Pure Regurgitation: Overcoming Anatomical and Technical Barriers.PMC12426643Choi CZgheib AKandah FFeghaly JSuma VfalseTransfemoral TAVR in a Quadricuspid Aortic Valve With Pure Regurgitation: Overcoming Anatomical and Technical Barriers.We present a case of successful transfemoral transcatheter aortic valve replacement for a rare quadricuspid aortic valve with pure aortic regurgitation. Procedural challenges included identifying the annular plane, determining the appropriate deployment view, annular sizing, the absence of annular calcium, and the lack of a dedicated transcatheter device for pure aortic regurgitation.2025-01-01T00:00:00Z2025 Sep2026-04-08T19:16:05.099Z2026-04-08T12:11:11.127ZS-EPMC124266434091283810.1016/j.jaccas.2025.104879