{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["30(26)"],"submitter":["Panichella G"],"pubmed_abstract":["<h4>Background</h4>Single coronary artery is a rare congenital anomaly. Its coexistence with coronary artery fistula is exceedingly uncommon.<h4>Case summary</h4>A 61-year-old woman with no cardiovascular risk factors underwent her first cardiological evaluation after incidental detection of atrial fibrillation. Imaging revealed a markedly dilated single coronary artery originating from the left coronary sinus, with a large fistula to the pulmonary artery trunk. Despite atrial enlargement and moderate mitral and tricuspid regurgitation, the patient was asymptomatic with preserved ventricular function. A conservative management strategy with close follow-up was adopted after multidisciplinary discussion.<h4>Discussion</h4>Management of rare coronary anomalies should be individualized. While surgery is recommended in symptomatic patients or those with evidence of ischemia, asymptomatic individuals may be managed conservatively; however, signs of adverse cardiac remodeling should prompt early reconsideration of intervention.<h4>Take-home message</h4>Conservative follow-up may be appropriate in asymptomatic patients with complex coronary anomalies, but progressive structural changes warrant timely reassessment of surgical options."],"journal":["JACC. Case reports"],"pagination":["104875"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12426679"],"repository":["biostudies-literature"],"pubmed_title":["A Rare Case of Single Coronary Artery With Pulmonary Artery Fistula."],"pmcid":["PMC12426679"],"pubmed_authors":["Panichella G","Spaziani G","Olivotto I","Favilli S","Padeletti M"],"additional_accession":[]},"is_claimable":false,"name":"A Rare Case of Single Coronary Artery With Pulmonary Artery Fistula.","description":"<h4>Background</h4>Single coronary artery is a rare congenital anomaly. Its coexistence with coronary artery fistula is exceedingly uncommon.<h4>Case summary</h4>A 61-year-old woman with no cardiovascular risk factors underwent her first cardiological evaluation after incidental detection of atrial fibrillation. Imaging revealed a markedly dilated single coronary artery originating from the left coronary sinus, with a large fistula to the pulmonary artery trunk. Despite atrial enlargement and moderate mitral and tricuspid regurgitation, the patient was asymptomatic with preserved ventricular function. A conservative management strategy with close follow-up was adopted after multidisciplinary discussion.<h4>Discussion</h4>Management of rare coronary anomalies should be individualized. While surgery is recommended in symptomatic patients or those with evidence of ischemia, asymptomatic individuals may be managed conservatively; however, signs of adverse cardiac remodeling should prompt early reconsideration of intervention.<h4>Take-home message</h4>Conservative follow-up may be appropriate in asymptomatic patients with complex coronary anomalies, but progressive structural changes warrant timely reassessment of surgical options.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-04-08T19:52:25.038Z","creation":"2026-04-08T14:35:40.183Z"},"accession":"S-EPMC12426679","cross_references":{"pubmed":["40912840"],"doi":["10.1016/j.jaccas.2025.104875"]}}