biostudies-literatureLiu HProject for Improving the Scientific Research Ability of Key Disciplines under Construction in Guangdong Province in 2024Characteristic innovation projects of universities in Guangdong Provincethe National Key R&D Program of China2983https://www.ebi.ac.uk/biostudies/studies/S-EPMC12428359biostudies-literatureUnknown14(17)Xanthones from mangosteen pericarp (MP) are bioactive compounds with promising pharmaceutical and nutraceutical applications. However, their efficient and selective extraction using environmentally friendly solvents remains a challenge. This study aimed to evaluate tricaprylin (C8) and tricaprin (C10) as novel green co-extractants in supercritical carbon dioxide (scCO₂) extraction for the recovery of xanthones from MP, using a mass ratio of C8:C10 = 0.64:0.36, hereafter referred to as C8/C10, and to model extraction kinetics for process design and scale-up. Extraction performance was investigated using different C8/C10-MP mass ratios and scCO₂ conditions at temperatures of 60 °C and 70 °C and pressures of 250 bar, 350 bar, and 450 bar. A pseudo-first-order kinetic modFoods (Basel, Switzerland)Green Co-Extractant-Assisted Supercritical CO<sub>2</sub> Extraction of Xanthones from Mangosteen Pericarp Using Tricaprylin and Tricaprin Mixtures.PMC124283592023YFF11040042024ZDJS0902024KTSCX151Liu HChong GHRen JSuleiman NBStanslas JfalseGreen Co-Extractant-Assisted Supercritical CO<sub>2</sub> Extraction of Xanthones from Mangosteen Pericarp Using Tricaprylin and Tricaprin Mixtures.Xanthones from mangosteen pericarp (MP) are bioactive compounds with promising pharmaceutical and nutraceutical applications. However, their efficient and selective extraction using environmentally friendly solvents remains a challenge. This study aimed to evaluate tricaprylin (C8) and tricaprin (C10) as novel green co-extractants in supercritical carbon dioxide (scCO₂) extraction for the recovery of xanthones from MP, using a mass ratio of C8:C10 = 0.64:0.36, hereafter referred to as C8/C10, and to model extraction kinetics for process design and scale-up. Extraction performance was investigated using different C8/C10-MP mass ratios and scCO₂ conditions at temperatures of 60 °C and 70 °C and pressures of 250 bar, 350 bar, and 450 bar. A pseudo-first-order kinetic mod2025-01-01T00:00:00Z2025 Aug2026-04-08T19:11:45.4Z2026-04-08T12:03:06.595ZS-EPMC124283594094109910.3390/foods14172983