{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17(17)"],"submitter":["Sanmartin-Sanchez A"],"pubmed_abstract":["<b>Background/Objetives</b>: Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with poor prognosis. Nutritional disorders, particularly cachexia, significantly impact morbidity and mortality in IPF but remain under-investigated. This study aimed to characterize cachexia phenotypes in IPF through morphofunctional assessment (MFA) and to evaluate their prognostic relevance, including the role of mitochondrial biomarkers. <b>Methods</b>: In this prospective bicenter study, 85 IPF patients underwent MFA including bioelectrical impedance vector analysis (BIVA), nutritional ultrasound (NU), and T12-level computed tomography (T12-CT) for body composition. Functional and strength assessments included timed up and go test (TUG) and handgrip strength (HGS), respectively."],"journal":["Nutrients"],"pagination":["2739"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12430740"],"repository":["biostudies-literature"],"pubmed_title":["Cachexia Phenotyping Through Morphofunctional Assessment and Mitocondrial Biomarkers (GDF-15 and PGC-1α) in Idiopathic Pulmonary Fibrosis."],"pmcid":["PMC12430740"],"pubmed_authors":["Olivares-Alcolea J","Cornejo-Pareja I","Garrido-Sanchez L","Sanchez-Garcia A","Vegas-Aguilar I","Cabrera-Cesar E","Espildora-Hernandez F","Murri M","Tinahones FJ","Velasco-Garrido JL","Guirado-Pelaez P","Fernandez-Jimenez R","Amaya-Campos MDM","Villaplana-Garcia M","Garcia-Almeida JM","Simon-Frapolli VJ","Sanmartin-Sanchez A","Vidal-Suarez A"],"additional_accession":[]},"is_claimable":false,"name":"Cachexia Phenotyping Through Morphofunctional Assessment and Mitocondrial Biomarkers (GDF-15 and PGC-1α) in Idiopathic Pulmonary Fibrosis.","description":"<b>Background/Objetives</b>: Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with poor prognosis. Nutritional disorders, particularly cachexia, significantly impact morbidity and mortality in IPF but remain under-investigated. This study aimed to characterize cachexia phenotypes in IPF through morphofunctional assessment (MFA) and to evaluate their prognostic relevance, including the role of mitochondrial biomarkers. <b>Methods</b>: In this prospective bicenter study, 85 IPF patients underwent MFA including bioelectrical impedance vector analysis (BIVA), nutritional ultrasound (NU), and T12-level computed tomography (T12-CT) for body composition. Functional and strength assessments included timed up and go test (TUG) and handgrip strength (HGS), respectively.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-04-23T03:23:03.877Z","creation":"2026-04-23T03:11:57.056Z"},"accession":"S-EPMC12430740","cross_references":{"pubmed":["40944130"],"doi":["10.3390/nu17172739"]}}