biostudies-literatureUnknown20(9)Sesay U<h4>Background</h4>Immunization is a cornerstone of public health, preventing numerous vaccine-preventable diseases. However, disparities in immunization coverage persist globally, particularly in low-income countries like Sierra Leone. This study aims to examine the trends and socioeconomic and geographic inequalities in full immunization coverage among two-year-olds in Sierra Leone between 2008 and 2019.<h4>Methods</h4>This study utilised data from the Sierra Leone Demographic Health Surveys conducted in 2008, 2013, and 2019. The Health Equity Assessment Toolkit software developed by the World Health Organisation was used to calculate various inequality measures, including Difference, Ratio, Population-Attributable Risk, and Population-Attributable Fraction. An assessment of inequality wPloS onee0329572https://www.ebi.ac.uk/biostudies/studies/S-EPMC12431341biostudies-literatureTrends and inequalities in full immunization coverage among two-year-olds in Sierra Leone, 2008-2019.PMC12431341Benya HOsborne ABangura CSesay UAhinkorah BOfalseTrends and inequalities in full immunization coverage among two-year-olds in Sierra Leone, 2008-2019.<h4>Background</h4>Immunization is a cornerstone of public health, preventing numerous vaccine-preventable diseases. However, disparities in immunization coverage persist globally, particularly in low-income countries like Sierra Leone. This study aims to examine the trends and socioeconomic and geographic inequalities in full immunization coverage among two-year-olds in Sierra Leone between 2008 and 2019.<h4>Methods</h4>This study utilised data from the Sierra Leone Demographic Health Surveys conducted in 2008, 2013, and 2019. The Health Equity Assessment Toolkit software developed by the World Health Organisation was used to calculate various inequality measures, including Difference, Ratio, Population-Attributable Risk, and Population-Attributable Fraction. An assessment of inequality w2025-01-01T00:00:00Z20252026-06-01T12:09:40.689Z2026-04-08T12:03:48.47ZS-EPMC124313414093893510.1371/journal.pone.0329572