biostudies-literatureUnknown14(8)Chan C<h4>Background and objective</h4>Urinary pH is an important factor in the preventative management of kidney stones. A variety of options are available for modulating urinary pH, including pharmaceuticals, over the counter (OTC) formulations [such as stone specific OTCs, complementary and alternative medicines (CAMs), and home remedies], and dietary modifications. These options can be overwhelming for both providers and patients and vary with regards to cost, convenience, and efficacy. In the absence of a consolidated central source of information for patients and physicians to reference, our study aims to summarize and analyze the effectiveness of these various treatment approaches to provide a more comprehensive understanding of how common interventions alter urinary pH.<h4>Methods</h4>ThTranslational andrology and urology2428-2438https://www.ebi.ac.uk/biostudies/studies/S-EPMC12433178biostudies-literatureModulators of urinary pH in the context of urinary stone disease: a literature review.PMC12433178Stoller MSui WBreeggemann MCChan CfalseModulators of urinary pH in the context of urinary stone disease: a literature review.<h4>Background and objective</h4>Urinary pH is an important factor in the preventative management of kidney stones. A variety of options are available for modulating urinary pH, including pharmaceuticals, over the counter (OTC) formulations [such as stone specific OTCs, complementary and alternative medicines (CAMs), and home remedies], and dietary modifications. These options can be overwhelming for both providers and patients and vary with regards to cost, convenience, and efficacy. In the absence of a consolidated central source of information for patients and physicians to reference, our study aims to summarize and analyze the effectiveness of these various treatment approaches to provide a more comprehensive understanding of how common interventions alter urinary pH.<h4>Methods</h4>Th2025-01-01T00:00:00Z2025 Aug2026-06-01T15:43:57.461Z2026-04-08T13:44:57.448ZS-EPMC124331784094943310.21037/tau-2025-275