{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Cheng G"],"pubmed_abstract":["<h4>Objective</h4>This study aimed to explore the relationship between early adulthood obesity and sarcopenic obesity (SO) among middle-aged and older adults in the United States.<h4>Methods</h4>This retrospective study was conducted involving adults aged 50-69 years in the United States. Data were extracted from the National Health and Nutrition Examination Survey (NHANES) during the periods 1999-2006 and 2011-2018. Height and weight at the age of 25 years were measured. Body mass index (BMI) at the age of 25 years (BMI<sub>25</sub>) was calculated. Healthy weight, overweight, and obesity at the age of 25 years (healthy weight<sub>25</sub>, overweight<sub>25</sub>, and obesity<sub>25</sub>) were defined as BMI<sub>25</sub> 18.5 to less than 25 kg/m<sup>2</sup>, 25 to less than 30 kg/m<sup>2</sup>, and 30 kg/m<sup>2</sup> or greater, respectively. SO was determined by dividing appendicular skeletal muscle mass by weight (ASM/Wt) and percentage of fat mass [FM (%)].<h4>Results</h4>The prevalence of SO was 5.4, 8.5, and 16.5% in healthy weight<sub>25</sub>, overweight<sub>25</sub>, and obesity<sub>25</sub> groups, respectively. After adjusting for confounding factors, the prevalence of SO in the overweight<sub>25</sub> group and the obesity<sub>25</sub> group was 1.161 times (95%CI: 0.898-1.500, <i>p</i> = 0.254) and 2.286 times (95%CI: 1.651-3.165, <i>p</i> < 0.001) higher, respectively, compared to the healthy weight<sub>25</sub> group.<h4>Conclusion</h4>This study demonstrates that obesity in early adulthood is closely associated with an increased risk of sarcopenic obesity among middle-aged and older adults."],"journal":["Frontiers in public health"],"pagination":["1609325"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12433845"],"repository":["biostudies-literature"],"pubmed_title":["The relationship between early adulthood obesity and sarcopenic obesity among middle-aged and older adults in the United States."],"pmcid":["PMC12433845"],"pubmed_authors":["Wang C","Cheng G","Zhou Y","Wang Y","Xu J"],"additional_accession":[]},"is_claimable":false,"name":"The relationship between early adulthood obesity and sarcopenic obesity among middle-aged and older adults in the United States.","description":"<h4>Objective</h4>This study aimed to explore the relationship between early adulthood obesity and sarcopenic obesity (SO) among middle-aged and older adults in the United States.<h4>Methods</h4>This retrospective study was conducted involving adults aged 50-69 years in the United States. Data were extracted from the National Health and Nutrition Examination Survey (NHANES) during the periods 1999-2006 and 2011-2018. Height and weight at the age of 25 years were measured. Body mass index (BMI) at the age of 25 years (BMI<sub>25</sub>) was calculated. Healthy weight, overweight, and obesity at the age of 25 years (healthy weight<sub>25</sub>, overweight<sub>25</sub>, and obesity<sub>25</sub>) were defined as BMI<sub>25</sub> 18.5 to less than 25 kg/m<sup>2</sup>, 25 to less than 30 kg/m<sup>2</sup>, and 30 kg/m<sup>2</sup> or greater, respectively. SO was determined by dividing appendicular skeletal muscle mass by weight (ASM/Wt) and percentage of fat mass [FM (%)].<h4>Results</h4>The prevalence of SO was 5.4, 8.5, and 16.5% in healthy weight<sub>25</sub>, overweight<sub>25</sub>, and obesity<sub>25</sub> groups, respectively. After adjusting for confounding factors, the prevalence of SO in the overweight<sub>25</sub> group and the obesity<sub>25</sub> group was 1.161 times (95%CI: 0.898-1.500, <i>p</i> = 0.254) and 2.286 times (95%CI: 1.651-3.165, <i>p</i> < 0.001) higher, respectively, compared to the healthy weight<sub>25</sub> group.<h4>Conclusion</h4>This study demonstrates that obesity in early adulthood is closely associated with an increased risk of sarcopenic obesity among middle-aged and older adults.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-04-08T19:53:49.996Z","creation":"2026-04-08T14:36:08.55Z"},"accession":"S-EPMC12433845","cross_references":{"pubmed":["40959626"],"doi":["10.3389/fpubh.2025.1609325"]}}