{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["20(9)"],"submitter":["Takagi Y"],"pubmed_abstract":["<h4>Purpose</h4>To investigate the concordance between angle-closure assessments based on GS-1 gonioscope images and those obtained with anterior-segment optical coherence tomography.<h4>Study design</h4>Retrospective clinical study.<h4>Methods</h4>We included 33 patients (53 eyes) who visited Chukyo Eye Clinic during 2020-2024, were suspected of having angle closure, and underwent anterior-segment optical coherence tomography (CASIA2 Advance STAR Analyzer) and GS-1 examinations. The 16-directional images captured with the GS-1 were divided into two halves, creating 32 directions, which were rearranged to correspond with those obtained via anterior-segment optical coherence tomography. Agreement between evaluations was analyzed using Cohen's κ, and the area under the receiver operating characteristic curve was evaluated. Anterior-segment optical coherence tomography images were manually corrected, and eyes with areas classified as \"narrow\" or \"closed\" were categorized as angle closure. With the GS-1, two glaucoma specialists independently reviewed the images. Areas in which the posterior trabecular meshwork was obscured in more than half of the image (Scheie classification grades III-IV) were judged indicative of angle closure.<h4>Results</h4>We included 1,660 directions from 53 eyes in the agreement analysis. The proportion of directions judged as angle closure was 57.0% with anterior-segment optical coherence tomography and 46.1% with the GS-1. Cohen's κ for inter-test agreement was 0.173 (95% confidence interval: 0.128-0.218), and the area under the receiver operating characteristic curve was 0.588 (95% confidence interval: 0.561-0.615).<h4>Conclusion</h4>Analyses using anterior-segment optical coherence tomography yielded more frequent classifications of angle closure than evaluations based on GS-1 gonioscopic images."],"journal":["PloS one"],"pagination":["e0332590"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12435641"],"repository":["biostudies-literature"],"pubmed_title":["Comparison of angle-closure detection between automated gonioscopy and anterior-segment optical coherence tomography."],"pmcid":["PMC12435641"],"pubmed_authors":["Takagi Y","Sakai Y","Yokoyama S","Ichikawa K","Morioka Y","Asano R"],"additional_accession":[]},"is_claimable":false,"name":"Comparison of angle-closure detection between automated gonioscopy and anterior-segment optical coherence tomography.","description":"<h4>Purpose</h4>To investigate the concordance between angle-closure assessments based on GS-1 gonioscope images and those obtained with anterior-segment optical coherence tomography.<h4>Study design</h4>Retrospective clinical study.<h4>Methods</h4>We included 33 patients (53 eyes) who visited Chukyo Eye Clinic during 2020-2024, were suspected of having angle closure, and underwent anterior-segment optical coherence tomography (CASIA2 Advance STAR Analyzer) and GS-1 examinations. The 16-directional images captured with the GS-1 were divided into two halves, creating 32 directions, which were rearranged to correspond with those obtained via anterior-segment optical coherence tomography. Agreement between evaluations was analyzed using Cohen's κ, and the area under the receiver operating characteristic curve was evaluated. Anterior-segment optical coherence tomography images were manually corrected, and eyes with areas classified as \"narrow\" or \"closed\" were categorized as angle closure. With the GS-1, two glaucoma specialists independently reviewed the images. Areas in which the posterior trabecular meshwork was obscured in more than half of the image (Scheie classification grades III-IV) were judged indicative of angle closure.<h4>Results</h4>We included 1,660 directions from 53 eyes in the agreement analysis. The proportion of directions judged as angle closure was 57.0% with anterior-segment optical coherence tomography and 46.1% with the GS-1. Cohen's κ for inter-test agreement was 0.173 (95% confidence interval: 0.128-0.218), and the area under the receiver operating characteristic curve was 0.588 (95% confidence interval: 0.561-0.615).<h4>Conclusion</h4>Analyses using anterior-segment optical coherence tomography yielded more frequent classifications of angle closure than evaluations based on GS-1 gonioscopic images.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-06-01T14:04:00.296Z","creation":"2026-04-08T13:16:34.618Z"},"accession":"S-EPMC12435641","cross_references":{"pubmed":["40953048"],"doi":["10.1371/journal.pone.0332590"]}}