{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bodin J"],"funding":["Agence Nationale de la Recherche","Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail","industrial companies","French national health insurance fund"],"pagination":["e0329324"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12435683"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(9)"],"pubmed_abstract":["<h4>Objective</h4>To study the association between occupational co-exposure to biomechanical risk factors, potentially neurotoxic chemicals and carpal tunnel syndrome (CTS) in a large cohort of French workers, using two methods to estimate chemical exposure: job-exposure matrices (JEM) and self-reported exposure.<h4>Methods</h4>A randomly selected sample of adults were included between 2012 and 2018 in the French cohort CONSTANCES. Self-reported CTS was assessed using the first self-administered follow-up questionnaire, sent out approximately one year after baseline. Occupational exposure to biomechanical risk factors was assessed using self-administered questionnaire completed at inclusion. Lifetime occupational exposure to chemicals was assessed using two different methods: with JEMs and"],"journal":["PloS one"],"pubmed_title":["Carpal tunnel syndrome and occupational co-exposure to biomechanical factors and neurotoxic chemicals using job-exposure matrices and self-reported exposure: Findings from the Constances cohort."],"pmcid":["PMC12435683"],"funding_grant_id":["ANSES-21-EST-030","ANR-11-INBS-0002"],"pubmed_authors":["Bodin J","Bonvallot N","Gilbert F","Descatha A","Fadel M","Rapicault C","Evanoff B","Goldberg M","Roquelaure Y","Zins M"],"additional_accession":[]},"is_claimable":false,"name":"Carpal tunnel syndrome and occupational co-exposure to biomechanical factors and neurotoxic chemicals using job-exposure matrices and self-reported exposure: Findings from the Constances cohort.","description":"<h4>Objective</h4>To study the association between occupational co-exposure to biomechanical risk factors, potentially neurotoxic chemicals and carpal tunnel syndrome (CTS) in a large cohort of French workers, using two methods to estimate chemical exposure: job-exposure matrices (JEM) and self-reported exposure.<h4>Methods</h4>A randomly selected sample of adults were included between 2012 and 2018 in the French cohort CONSTANCES. Self-reported CTS was assessed using the first self-administered follow-up questionnaire, sent out approximately one year after baseline. Occupational exposure to biomechanical risk factors was assessed using self-administered questionnaire completed at inclusion. Lifetime occupational exposure to chemicals was assessed using two different methods: with JEMs and","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-04-08T19:55:20.425Z","creation":"2026-04-08T14:36:26.153Z"},"accession":"S-EPMC12435683","cross_references":{"pubmed":["40953005"],"doi":["10.1371/journal.pone.0329324"]}}