{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Barr EA"],"funding":["National Institute of Allergy and Infectious Diseases","Eunice Kennedy Shriver National Institute of Child Health and Human Development","NIAID NIH HHS"],"pubmed_abstract":["<i>Background:</i> Primary results of the International Maternal Pediatric Adolescent AIDS Clinical Trials Network (IMPAACT) 2002 trial showed that cognitive behavioural therapy (CBT) and medication management algorithm (MMA) (COMB-R) significantly improved depression in youth with HIV (YWH) compared with enhanced standard care (ESC). Acceptability and satisfaction were examined among study participants and clinicians.<i>Method:</i> Between March 2017 and March 2019, 13 U.S. sites enrolled YWH, aged 12-24, diagnosed with nonpsychotic depression. Sites were randomised to either COMB-R (CBT by a therapist and licensed prescriber) or ESC (standard psychotherapy and medication management). After the intervention (week 24), participants, prescribers, and therapists rated acceptability and satis"],"journal":["Journal of child and adolescent mental health"],"pagination":["1-16"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12439113"],"repository":["biostudies-literature"],"pubmed_title":["Participant acceptability and clinician satisfaction of cognitive behavioural therapy and medication management algorithm compared with enhanced standard care for treatment of depression among youth with HIV."],"pmcid":["PMC12439113"],"funding_grant_id":["UM1 AI068632","UM1 AI106716","P30 AI042853","HHSN275201800001I","UM1 AI068616","UM1AI068616-15 (IMPAACT SDMC)"],"pubmed_authors":["Townley E","Barr EA","Kennard BD","Emslie GJ","Knowles K","Buisson S","Deville JG","Shapiro DE","Bergam L","Shikora M","Brown LK","Krotje C","Gillespie SL","Baltrusaitis K"],"additional_accession":[]},"is_claimable":false,"name":"Participant acceptability and clinician satisfaction of cognitive behavioural therapy and medication management algorithm compared with enhanced standard care for treatment of depression among youth with HIV.","description":"<i>Background:</i> Primary results of the International Maternal Pediatric Adolescent AIDS Clinical Trials Network (IMPAACT) 2002 trial showed that cognitive behavioural therapy (CBT) and medication management algorithm (MMA) (COMB-R) significantly improved depression in youth with HIV (YWH) compared with enhanced standard care (ESC). Acceptability and satisfaction were examined among study participants and clinicians.<i>Method:</i> Between March 2017 and March 2019, 13 U.S. sites enrolled YWH, aged 12-24, diagnosed with nonpsychotic depression. Sites were randomised to either COMB-R (CBT by a therapist and licensed prescriber) or ESC (standard psychotherapy and medication management). After the intervention (week 24), participants, prescribers, and therapists rated acceptability and satis","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-06-01T15:49:26.975Z","creation":"2026-04-08T13:49:00.8Z"},"accession":"S-EPMC12439113","cross_references":{"pubmed":["39550758"],"doi":["10.2989/17280583.2024.2387632"]}}