{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Wang G"],"pubmed_abstract":["<h4>Background</h4>Adenovirus pneumonia presents a significant challenge in pediatric care, with severe children leading to significant morbidity. The study evaluated the combined prognostic value of serum Heparin Binding Protein (HBP), Tumor Necrosis Factor-alpha (TNF-α), Interleukin-6 (IL-6), platelet count (PLT), and C-Reactive Protein (CRP) levels in assessing the condition and prognosis of children with adenovirus pneumonia.<h4>Methods</h4>This retrospective study analyzed children with adenoviral pneumonia at our hospital from March 2019 to December 2024. Serum levels of HBP, TNF-α, IL-6, PLT, and CRP were measured. Participants were divided into non-severe and severe groups, and further into good and poor prognosis groups, based on clinical criteria and complications. Statistical an"],"journal":["Frontiers in pediatrics"],"pagination":["1620206"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12440316"],"repository":["biostudies-literature"],"pubmed_title":["The value of combined examination of serum serum heparin binding protein, tumor necrosis factor alpha, interleukin-6, platelet count, and c-reactive protein in evaluating the condition and prognosis of children with adenovirus pneumonia."],"pmcid":["PMC12440316"],"pubmed_authors":["Liu J","Cao S","Wang G","Yu X"],"additional_accession":[]},"is_claimable":false,"name":"The value of combined examination of serum serum heparin binding protein, tumor necrosis factor alpha, interleukin-6, platelet count, and c-reactive protein in evaluating the condition and prognosis of children with adenovirus pneumonia.","description":"<h4>Background</h4>Adenovirus pneumonia presents a significant challenge in pediatric care, with severe children leading to significant morbidity. The study evaluated the combined prognostic value of serum Heparin Binding Protein (HBP), Tumor Necrosis Factor-alpha (TNF-α), Interleukin-6 (IL-6), platelet count (PLT), and C-Reactive Protein (CRP) levels in assessing the condition and prognosis of children with adenovirus pneumonia.<h4>Methods</h4>This retrospective study analyzed children with adenoviral pneumonia at our hospital from March 2019 to December 2024. Serum levels of HBP, TNF-α, IL-6, PLT, and CRP were measured. Participants were divided into non-severe and severe groups, and further into good and poor prognosis groups, based on clinical criteria and complications. Statistical an","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-06-03T03:00:45.314Z","creation":"2026-04-23T03:13:40.998Z"},"accession":"S-EPMC12440316","cross_references":{"pubmed":["40963970"],"doi":["10.3389/fped.2025.1620206"]}}