{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Chen X"],"pubmed_abstract":["<h4>Objective</h4>This study aims to examine the variations in resistance genes, virulence genes, and drug susceptibility between carbapenem-resistant and carbapenem-susceptible <i>Acinetobacter baumannii</i> (CR-AB and CS-AB). Additionally, it seeks to assess the influence of efflux pump inhibitors on drug susceptibility, in order to provide new antimicrobial treatment strategies for CR-AB infections in the intensive care unit (ICU).<h4>Methods</h4>A retrospective study was undertaken involving 39 <i>A. baumannii</i> (<i>A. baumannii</i>) strains isolated from the ICU of Li Huili Hospital, affiliated with Ningbo University, during the period from January to December 2023. Of these strains, 18 were classified as CR-AB and 21 as CS-AB. The minimum inhibitory concentrations (MICs) of commonl"],"journal":["Frontiers in microbiology"],"pagination":["1646319"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12440978"],"repository":["biostudies-literature"],"pubmed_title":["Molecular characterization of carbapenem-resistant and carbapenem-sensitive &lt;i&gt;Acinetobacter baumannii&lt;/i&gt; isolates from an intensive care unit in Ningbo, China."],"pmcid":["PMC12440978"],"pubmed_authors":["Zhang W","Li H","Wang F","Chen X","Gao H","Jiang M","Tu Y","Zhao Y"],"additional_accession":[]},"is_claimable":false,"name":"Molecular characterization of carbapenem-resistant and carbapenem-sensitive &lt;i&gt;Acinetobacter baumannii&lt;/i&gt; isolates from an intensive care unit in Ningbo, China.","description":"<h4>Objective</h4>This study aims to examine the variations in resistance genes, virulence genes, and drug susceptibility between carbapenem-resistant and carbapenem-susceptible <i>Acinetobacter baumannii</i> (CR-AB and CS-AB). Additionally, it seeks to assess the influence of efflux pump inhibitors on drug susceptibility, in order to provide new antimicrobial treatment strategies for CR-AB infections in the intensive care unit (ICU).<h4>Methods</h4>A retrospective study was undertaken involving 39 <i>A. baumannii</i> (<i>A. baumannii</i>) strains isolated from the ICU of Li Huili Hospital, affiliated with Ningbo University, during the period from January to December 2023. Of these strains, 18 were classified as CR-AB and 21 as CS-AB. The minimum inhibitory concentrations (MICs) of commonl","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-06-03T12:06:51.867Z","creation":"2026-04-27T03:11:32.313Z"},"accession":"S-EPMC12440978","cross_references":{"pubmed":["40969439"],"doi":["10.3389/fmicb.2025.1646319"]}}