biostudies-literatureUnknown16Chen X<h4>Objective</h4>This study aims to examine the variations in resistance genes, virulence genes, and drug susceptibility between carbapenem-resistant and carbapenem-susceptible <i>Acinetobacter baumannii</i> (CR-AB and CS-AB). Additionally, it seeks to assess the influence of efflux pump inhibitors on drug susceptibility, in order to provide new antimicrobial treatment strategies for CR-AB infections in the intensive care unit (ICU).<h4>Methods</h4>A retrospective study was undertaken involving 39 <i>A. baumannii</i> (<i>A. baumannii</i>) strains isolated from the ICU of Li Huili Hospital, affiliated with Ningbo University, during the period from January to December 2023. Of these strains, 18 were classified as CR-AB and 21 as CS-AB. The minimum inhibitory concentrations (MICs) of commonlFrontiers in microbiology1646319https://www.ebi.ac.uk/biostudies/studies/S-EPMC12440978biostudies-literatureMolecular characterization of carbapenem-resistant and carbapenem-sensitive <i>Acinetobacter baumannii</i> isolates from an intensive care unit in Ningbo, China.PMC12440978Zhang WLi HWang FChen XGao HJiang MTu YZhao YfalseMolecular characterization of carbapenem-resistant and carbapenem-sensitive <i>Acinetobacter baumannii</i> isolates from an intensive care unit in Ningbo, China.<h4>Objective</h4>This study aims to examine the variations in resistance genes, virulence genes, and drug susceptibility between carbapenem-resistant and carbapenem-susceptible <i>Acinetobacter baumannii</i> (CR-AB and CS-AB). Additionally, it seeks to assess the influence of efflux pump inhibitors on drug susceptibility, in order to provide new antimicrobial treatment strategies for CR-AB infections in the intensive care unit (ICU).<h4>Methods</h4>A retrospective study was undertaken involving 39 <i>A. baumannii</i> (<i>A. baumannii</i>) strains isolated from the ICU of Li Huili Hospital, affiliated with Ningbo University, during the period from January to December 2023. Of these strains, 18 were classified as CR-AB and 21 as CS-AB. The minimum inhibitory concentrations (MICs) of commonl2025-01-01T00:00:00Z20252026-06-03T12:06:51.867Z2026-04-27T03:11:32.313ZS-EPMC124409784096943910.3389/fmicb.2025.1646319