{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Umurzokov M"],"funding":["National Research Foundation of Korea"],"pagination":["7219-7231"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12441759"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["81(10)"],"pubmed_abstract":["Background
The research focused on developing effective photosystem II (PSII) inhibiting triazine-derived herbicidal compounds from the internal chemical library. Initially, the compounds were screened for their herbicidal activity using Spirodela polyrhiza (SPIPO) assays. Subsequently, compounds with stronger activity were synthesized on a gram scale and further investigated for their phytotoxicity, mobility, and mode of action.Results
In the SPIPO screenings, two compounds, K-31706 and K-31487, showed superior efficacy at concentrations exceeding 0.4 μm, surpassing the commonly used PSII inhibition herbicide, atrazine. Both compounds showed promising performance, especially in pre-emergence applications under greenhouse conditions, with the application rate causing 50% bi"],"journal":["Pest management science"],"pubmed_title":["Discovery of new PSII inhibitors: systematic investigation for herbicidal activity screening, properties, and mode of action."],"pmcid":["PMC12441759"],"funding_grant_id":["NRF-2019R1C1C1004970","NRF‐2019R1C1C1004970"],"pubmed_authors":["Kim D","Park KW","Cho KM","Lim HN","Umurzokov M","Kim JS","Choi JS"],"additional_accession":[]},"is_claimable":false,"name":"Discovery of new PSII inhibitors: systematic investigation for herbicidal activity screening, properties, and mode of action.","description":"Background
The research focused on developing effective photosystem II (PSII) inhibiting triazine-derived herbicidal compounds from the internal chemical library. Initially, the compounds were screened for their herbicidal activity using Spirodela polyrhiza (SPIPO) assays. Subsequently, compounds with stronger activity were synthesized on a gram scale and further investigated for their phytotoxicity, mobility, and mode of action.Results
In the SPIPO screenings, two compounds, K-31706 and K-31487, showed superior efficacy at concentrations exceeding 0.4 μm, surpassing the commonly used PSII inhibition herbicide, atrazine. Both compounds showed promising performance, especially in pre-emergence applications under greenhouse conditions, with the application rate causing 50% bi","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-07-15T06:51:22.802Z","creation":"2026-06-30T03:25:03.883Z"},"accession":"S-EPMC12441759","cross_references":{"pubmed":["40673640"],"doi":["10.1002/ps.70071"]}}