{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bernardes JPRA"],"funding":["NIAID NIH HHS"],"pagination":["e0033525"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12442369"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["91(9)"],"pubmed_abstract":["Caves serve as natural reservoirs for diverse microbial species due to their unique biotic and abiotic conditions. <i>Histoplasma</i> spp. is frequently associated with guano-enriched soil, low luminosity, and high humidity, particularly in Latin America, a region highly endemic for histoplasmosis. Despite the continent's diverse biomes, local environmental and host distributions of <i>Histoplasma</i> remain poorly understood. To address this knowledge gap, we conducted a <i>Histoplasma</i>-specific quantitative PCR assay targeting the <i>hc100</i> gene on guano samples from seven bat-inhabited caves and tissue samples from 74 bats of nine species in the Federal District of Brazil and surrounding regions. We detected <i>Histoplasma</i> DNA in 16 of 80 soil samples (20%) and in 33 bats repr"],"journal":["Applied and environmental microbiology"],"pubmed_title":["Mapping &lt;i&gt;Histoplasma&lt;/i&gt; spp. in bats and cave ecosystems: evidence from midwestern Brazil."],"pmcid":["PMC12442369"],"funding_grant_id":["R01 AI153523"],"pubmed_authors":["Paes HC","Felipe MSS","Bueno-Rocha ID","de Oliveira LS","Charneau S","Teixeira MdM","Bernardes JPRA","Alves LGdB","Paternina CEM","Silva Pereira I","Arenas PHR","Aguiar LMdS","Tenorio BG","Zancope-Oliveira RM","Nicola AM","Lucas J","Magalhaes ED","de Sousa HR","Erazo FAH","Matute DR","da Silva RKM"],"additional_accession":[]},"is_claimable":false,"name":"Mapping &lt;i&gt;Histoplasma&lt;/i&gt; spp. in bats and cave ecosystems: evidence from midwestern Brazil.","description":"Caves serve as natural reservoirs for diverse microbial species due to their unique biotic and abiotic conditions. <i>Histoplasma</i> spp. is frequently associated with guano-enriched soil, low luminosity, and high humidity, particularly in Latin America, a region highly endemic for histoplasmosis. Despite the continent's diverse biomes, local environmental and host distributions of <i>Histoplasma</i> remain poorly understood. To address this knowledge gap, we conducted a <i>Histoplasma</i>-specific quantitative PCR assay targeting the <i>hc100</i> gene on guano samples from seven bat-inhabited caves and tissue samples from 74 bats of nine species in the Federal District of Brazil and surrounding regions. We detected <i>Histoplasma</i> DNA in 16 of 80 soil samples (20%) and in 33 bats repr","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-03T11:18:32.683Z","creation":"2026-05-29T03:06:04.63Z"},"accession":"S-EPMC12442369","cross_references":{"pubmed":["40793772"],"doi":["10.1128/aem.00335-25"]}}