{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Winhusen TJ"],"funding":["National Institute on Drug Abuse Clinical Trials Network","Eunice Kennedy Shriver National Institute of Child Health and Human Development","NIDA NIH HHS","University of Cincinnati","National Institutes of Health","National Institute of Child Health and Human Development"],"pagination":["112795"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12444429"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["275"],"pubmed_abstract":["<h4>Background</h4>Overdose is a leading cause of pregnancy-associated mortality in the US. Our personally-tailored opioid-overdose (OOD) and medication for opioid use disorder (MOUD) education intervention has been shown to significantly improve MOUD/OOD knowledge in out-of-treatment persons using illicit opioids. We evaluated the ability of the intervention modified for peripartum (pregnant or within one year postpartum) individuals, the personally-tailored OOD and MOUD education (TOME) intervention, to increase MOUD (primary) and OOD (key secondary) knowledge.<h4>Methods</h4>A six-site, two-arm, open-label, trial with 131 peripartum individuals receiving MOUD (methadone or buprenorphine) randomized to TOME, a 15-minute, computer-facilitated, individually-tailored intervention, or Contro"],"journal":["Drug and alcohol dependence"],"pubmed_title":["Personally-tailored opioid-overdose and medication for opioid use disorder (MOUD) education (TOME) significantly increases MOUD and overdose knowledge in peripartum individuals: Results from a randomized controlled pilot trial."],"pmcid":["PMC12444429"],"funding_grant_id":["UG1DA013720","U10 DA013732","UG1DA049436","UG1 DA013727","UG1 DA049444","UG1DA049444","UG1DA013727","UG1 DA049436","UG1 DA013732","UG1DA013732","UG1 DA013720"],"pubmed_authors":["Winhusen TJ","Rosa C","Dilawar M","Kropp F","Cochran G","Krans EE","Lofwall MR","Davies TH","Smid MC","Young JL","Lewis D","Hodgkins C"],"additional_accession":[]},"is_claimable":false,"name":"Personally-tailored opioid-overdose and medication for opioid use disorder (MOUD) education (TOME) significantly increases MOUD and overdose knowledge in peripartum individuals: Results from a randomized controlled pilot trial.","description":"<h4>Background</h4>Overdose is a leading cause of pregnancy-associated mortality in the US. Our personally-tailored opioid-overdose (OOD) and medication for opioid use disorder (MOUD) education intervention has been shown to significantly improve MOUD/OOD knowledge in out-of-treatment persons using illicit opioids. We evaluated the ability of the intervention modified for peripartum (pregnant or within one year postpartum) individuals, the personally-tailored OOD and MOUD education (TOME) intervention, to increase MOUD (primary) and OOD (key secondary) knowledge.<h4>Methods</h4>A six-site, two-arm, open-label, trial with 131 peripartum individuals receiving MOUD (methadone or buprenorphine) randomized to TOME, a 15-minute, computer-facilitated, individually-tailored intervention, or Contro","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-03T15:32:14.42Z","creation":"2026-06-01T03:06:08.841Z"},"accession":"S-EPMC12444429","cross_references":{"pubmed":["40700987"],"doi":["10.1016/j.drugalcdep.2025.112795"]}}