{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["5(9)"],"submitter":["Pantoja-Arevalo L"],"pubmed_abstract":["Muscle health has not been thoroughly analyzed in pediatric cystic fibrosis (CF) under elexacaftor/tezacaftor/ivacaftor (ETI) therapy together with exercise interventions in randomized controlled trials (RCTs). The aim of this study will be to determine the effects of a virtual live exercise training intervention on muscle health and cardiorespiratory fitness (CRF) variables in a pediatric population with CF under ETI therapy. The 'FIQMODE' Study (FIQ for CF in Spanish, or fibrosis quística; MOD for modulator therapy; and E for exercise) is a two-arm RCT to evaluate the feasibility and efficacy of a novel exercise intervention to improve the muscle health and quality of life (QoL) of children and adolescents with CF under ETI pharmacological therapies. The exercise group will follow a 16-w"],"journal":["Current protocols"],"pagination":["e70202"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12445441"],"repository":["biostudies-literature"],"pubmed_title":["Strength-Oriented Virtual Exercise Training Intervention in Children and Adolescents with Cystic Fibrosis Under CFTR Modulators (the FIQMODE Study): Study Protocol for a Randomized Controlled Trial."],"pmcid":["PMC12445441"],"pubmed_authors":["Pantoja-Arevalo L","Lopez-Neyra A","Sanz-Santiago V","Santiago-Dorrego C","Barcelo O","Morales-Tirado A","Ramirez-Castillejo C","De Vidania S","Rubio Alonso M","Yvert T","Iturriaga T","Perez-Ruiz M","Quesada-Gonzalez C","Gonzalez-Gross M","De Manuel Gomez C","Ruiz de Valbuena M"],"additional_accession":[]},"is_claimable":false,"name":"Strength-Oriented Virtual Exercise Training Intervention in Children and Adolescents with Cystic Fibrosis Under CFTR Modulators (the FIQMODE Study): Study Protocol for a Randomized Controlled Trial.","description":"Muscle health has not been thoroughly analyzed in pediatric cystic fibrosis (CF) under elexacaftor/tezacaftor/ivacaftor (ETI) therapy together with exercise interventions in randomized controlled trials (RCTs). The aim of this study will be to determine the effects of a virtual live exercise training intervention on muscle health and cardiorespiratory fitness (CRF) variables in a pediatric population with CF under ETI therapy. The 'FIQMODE' Study (FIQ for CF in Spanish, or fibrosis quística; MOD for modulator therapy; and E for exercise) is a two-arm RCT to evaluate the feasibility and efficacy of a novel exercise intervention to improve the muscle health and quality of life (QoL) of children and adolescents with CF under ETI pharmacological therapies. The exercise group will follow a 16-w","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-03T17:02:19.829Z","creation":"2026-05-30T03:06:29.875Z"},"accession":"S-EPMC12445441","cross_references":{"pubmed":["40966068"],"doi":["10.1002/cpz1.70202"]}}