{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["74(3)"],"submitter":["Juan L"],"pubmed_abstract":["Understanding gut microbiome diversity in endangered chimpanzees (<i>Pan troglodytes</i>) is crucial for their effective <i>ex situ</i> conservation. This study characterized the age-related dynamics of the fecal microbiota in captive juvenile (< 5 years), adolescent (5-10 years), and adult (> 15 years) chimpanzees reared in Shanghai and Hangzhou Zoos using 16S rRNA sequencing and demonstrated significant ontogenetic shifts in the microbiota composition. Alpha diversity peaked in adolescents (significantly higher Ace/Chao1/Observed Species; <i>p</i> < 0.05), with the greatest number of unique OTUs (1,139). Community structures significantly differed between the age groups (ANOSIM <i>R</i> = 0.121). Furthermore, the captive diets drove the fundamental restructuring of the core phyla. The Fi"],"journal":["Polish journal of microbiology"],"pagination":["363-373"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12445987"],"repository":["biostudies-literature"],"pubmed_title":["Age-Related Dynamics of Fecal Microbiota in the Captive Chimpanzee (&lt;i&gt;Pan troglodytes&lt;/i&gt;)."],"pmcid":["PMC12445987"],"pubmed_authors":["Juan L","You Y","Zhu Y","Yan N","Huang K","Wu H","Zhang W","Cheng S","Pan H","Zhang Y","Ye S","Lou YI","Zhan J","Yuan Y"],"additional_accession":[]},"is_claimable":false,"name":"Age-Related Dynamics of Fecal Microbiota in the Captive Chimpanzee (&lt;i&gt;Pan troglodytes&lt;/i&gt;).","description":"Understanding gut microbiome diversity in endangered chimpanzees (<i>Pan troglodytes</i>) is crucial for their effective <i>ex situ</i> conservation. This study characterized the age-related dynamics of the fecal microbiota in captive juvenile (< 5 years), adolescent (5-10 years), and adult (> 15 years) chimpanzees reared in Shanghai and Hangzhou Zoos using 16S rRNA sequencing and demonstrated significant ontogenetic shifts in the microbiota composition. Alpha diversity peaked in adolescents (significantly higher Ace/Chao1/Observed Species; <i>p</i> < 0.05), with the greatest number of unique OTUs (1,139). Community structures significantly differed between the age groups (ANOSIM <i>R</i> = 0.121). Furthermore, the captive diets drove the fundamental restructuring of the core phyla. The Fi","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-04-28T03:22:57.94Z","creation":"2026-04-28T03:11:47.051Z"},"accession":"S-EPMC12445987","cross_references":{"pubmed":["40967813"],"doi":["10.33073/pjm-2025-031"]}}