{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["4(10 Pt 2)"],"submitter":["Eligini S"],"pubmed_abstract":["<h4>Background</h4>Coronary artery bypass graft (CABG) surgery is performed in patients with complex multivessel coronary artery disease, but long-term graft occlusion remains a major limitation. The immature surfactant protein type-B (proSP-B) has emerged as a predictor of adverse cardiovascular outcomes.<h4>Objectives</h4>The purpose of this study was to examine the relationship between preoperative plasma proSP-B and graft occlusion 18 months post-CABG. The aims were to evaluate whether elevated proSP-B could predict graft occlusion and to assess its predictive value within a multivariable model for long-term graft patency.<h4>Methods</h4>We evaluated proSP-B in relation to graft occlusion in 40 patients with occluded grafts (cases) and 130 patients without occlusions (noncases), with 1"],"journal":["JACC. Advances"],"pagination":["102119"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12446526"],"repository":["biostudies-literature"],"pubmed_title":["Immature Surfactant Protein Type-B Associates With Graft Patency in Patients Undergoing Coronary Artery Bypass Grafting."],"pmcid":["PMC12446526"],"pubmed_authors":["Andreini D","Parolari A","Banfi C","Eligini S","Agostoni P","Gianazza E","Brocca L","Veglia F","Tremoli E","Polvani G","Papaianni GG","Pepi M","Cavallotti L"],"additional_accession":[]},"is_claimable":false,"name":"Immature Surfactant Protein Type-B Associates With Graft Patency in Patients Undergoing Coronary Artery Bypass Grafting.","description":"<h4>Background</h4>Coronary artery bypass graft (CABG) surgery is performed in patients with complex multivessel coronary artery disease, but long-term graft occlusion remains a major limitation. The immature surfactant protein type-B (proSP-B) has emerged as a predictor of adverse cardiovascular outcomes.<h4>Objectives</h4>The purpose of this study was to examine the relationship between preoperative plasma proSP-B and graft occlusion 18 months post-CABG. The aims were to evaluate whether elevated proSP-B could predict graft occlusion and to assess its predictive value within a multivariable model for long-term graft patency.<h4>Methods</h4>We evaluated proSP-B in relation to graft occlusion in 40 patients with occluded grafts (cases) and 130 patients without occlusions (noncases), with 1","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-03T15:36:49.121Z","creation":"2026-05-30T03:07:22.472Z"},"accession":"S-EPMC12446526","cross_references":{"pubmed":["40907377"],"doi":["10.1016/j.jacadv.2025.102119"]}}