{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ngo AT"],"funding":["Generalitat de Catalunya","Ministerio de Ciencia, Innovación y Universidades","Agencia Estatal de Investigación","\"La Caixa\" Foundation","National Research Foundation of Korea","HORIZON EUROPE Reforming and enhancing the European Research and Innovation system"],"pagination":["e2420492"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12447033"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["37(37)"],"pubmed_abstract":["Spin-crossover (SCO) molecular-based switches have shown promise across a range of applications since their discovery, including sensing, information storage, actuators, and displays. Yet limited processability remains a barrier to their real-world implementation, as traditional methods for integrating SCO materials into polymer matrices are often complex, expensive, and prone to producing uneven material distributions. Herein, we demonstrate how 3D flow-focusing chemistry enables unprecedented control for the direct fabrication of SCO composite materials, addressing key challenges in processability, scalability, and cost. By using a 3D coaxial flow-focusing microfluidic device, we simultaneously synthesize [Fe(Htrz)<sub>2</sub>(trz)](BF<sub>4</sub>) and achieve its homogeneous incorporati"],"journal":["Advanced materials (Deerfield Beach, Fla.)"],"pubmed_title":["On-the-Fly Synthesis of Freestanding Spin-Crossover Architectures With Tunable Magnetic Properties."],"pmcid":["PMC12447033"],"funding_grant_id":["PID2020‐116612RB‐C33","CEX2021‐001202","NRF-2022R1C1C1007338","2021 SGR 00270","LCF/BQ/PI24/12040015","101047081","CEX2021-001202","NRF‐2022R1C1C1007338","PID2020-116612RB-C33"],"pubmed_authors":["Diaz-Marcos J","Jang B","Ngo AT","Pons R","Palacios-Corella M","Aromi G","Puigmarti-Luis J","Sevim S","Pane S","Mayor TS","Aguila D","Vale JP","Mattera M"],"additional_accession":[]},"is_claimable":false,"name":"On-the-Fly Synthesis of Freestanding Spin-Crossover Architectures With Tunable Magnetic Properties.","description":"Spin-crossover (SCO) molecular-based switches have shown promise across a range of applications since their discovery, including sensing, information storage, actuators, and displays. Yet limited processability remains a barrier to their real-world implementation, as traditional methods for integrating SCO materials into polymer matrices are often complex, expensive, and prone to producing uneven material distributions. Herein, we demonstrate how 3D flow-focusing chemistry enables unprecedented control for the direct fabrication of SCO composite materials, addressing key challenges in processability, scalability, and cost. By using a 3D coaxial flow-focusing microfluidic device, we simultaneously synthesize [Fe(Htrz)<sub>2</sub>(trz)](BF<sub>4</sub>) and achieve its homogeneous incorporati","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-03T15:29:56.767Z","creation":"2026-04-29T03:12:41.843Z"},"accession":"S-EPMC12447033","cross_references":{"pubmed":["40511705"],"doi":["10.1002/adma.202420492"]}}