{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Eid MA"],"funding":["Society for Vascular Surgery","American College of Surgeons","National Heart, Lung, and Blood Institute","NHLBI NIH HHS","National Institutes of Health"],"pagination":["2069-2078.e5"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12450360"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["82(6)"],"pubmed_abstract":["Objective
The role of prophylactic carotid revascularization in asymptomatic patients aged ≥80 remains controversial. Current guidelines stipulate that asymptomatic older patients at \"higher risk of stroke\" on best medical therapy may still benefit from carotid intervention. Specifically, there is a widespread perception that a contralateral internal carotid artery (ICA) occlusion may confer an increased anatomical stroke risk, thus creating a surgical dilemma, particularly among older patients. The purpose of this analysis was to determine whether asymptomatic patients aged ≥80 years derive a stroke or survival benefit from prophylactic carotid revascularization in the setting of a contralateral internal carotid artery occlusion.Methods
We analyzed asymptomatic patients wi"],"journal":["Journal of vascular surgery"],"pubmed_title":["Surgical intervention among asymptomatic patients aged ≥80 with a contralateral carotid occlusion appears selectively warranted."],"pmcid":["PMC12450360"],"funding_grant_id":["K08 HL165087","K08HL165087"],"pubmed_authors":["Neal D","Huber TS","Scali ST","Perry I","Stone DH","Columbo JA","Eid MA","Cooper MA","Upchurch GR"],"additional_accession":[]},"is_claimable":false,"name":"Surgical intervention among asymptomatic patients aged ≥80 with a contralateral carotid occlusion appears selectively warranted.","description":"Objective
The role of prophylactic carotid revascularization in asymptomatic patients aged ≥80 remains controversial. Current guidelines stipulate that asymptomatic older patients at \"higher risk of stroke\" on best medical therapy may still benefit from carotid intervention. Specifically, there is a widespread perception that a contralateral internal carotid artery (ICA) occlusion may confer an increased anatomical stroke risk, thus creating a surgical dilemma, particularly among older patients. The purpose of this analysis was to determine whether asymptomatic patients aged ≥80 years derive a stroke or survival benefit from prophylactic carotid revascularization in the setting of a contralateral internal carotid artery occlusion.Methods
We analyzed asymptomatic patients wi","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-06T13:42:57.216Z","creation":"2026-05-31T03:09:32.986Z"},"accession":"S-EPMC12450360","cross_references":{"pubmed":["40769462"],"doi":["10.1016/j.jvs.2025.07.051"]}}