{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["80"],"submitter":["Peng C"],"pubmed_abstract":["<h4>Background</h4>This study explores potential associations between asthma and the Systemic Immune-Inflammation Index (SII).<h4>Methods</h4>The study primarily focuses on adults with complete data on SII and asthma from the National Health and Nutrition Examination Survey database (2015-2020). SII is calculated using the formula: platelet count × neutrophil count / lymphocyte count. The connection between SII and asthma was assessed through baseline feature analysis, weighted multivariate regression, subgroup analysis, and smooth curve fitting.<h4>Results</h4>A total of 13,334 participants were included, with 2045 individuals (15.34 %) having asthma. Subgroup analysis and interaction tests revealed no significant impact of gender, age, body mass index, vitamin C, magnesium, coronary hear"],"journal":["Clinics (Sao Paulo, Brazil)"],"pagination":["100779"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12450745"],"repository":["biostudies-literature"],"pubmed_title":["The hidden connection: systemic immune-inflammation index and its role in asthma."],"pmcid":["PMC12450745"],"pubmed_authors":["Peng C","Wang T","Gao D","Zhou Z"],"additional_accession":[]},"is_claimable":false,"name":"The hidden connection: systemic immune-inflammation index and its role in asthma.","description":"<h4>Background</h4>This study explores potential associations between asthma and the Systemic Immune-Inflammation Index (SII).<h4>Methods</h4>The study primarily focuses on adults with complete data on SII and asthma from the National Health and Nutrition Examination Survey database (2015-2020). SII is calculated using the formula: platelet count × neutrophil count / lymphocyte count. The connection between SII and asthma was assessed through baseline feature analysis, weighted multivariate regression, subgroup analysis, and smooth curve fitting.<h4>Results</h4>A total of 13,334 participants were included, with 2045 individuals (15.34 %) having asthma. Subgroup analysis and interaction tests revealed no significant impact of gender, age, body mass index, vitamin C, magnesium, coronary hear","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-03T17:20:03.29Z","creation":"2026-04-29T03:13:13.021Z"},"accession":"S-EPMC12450745","cross_references":{"pubmed":["40915180"],"doi":["10.1016/j.clinsp.2025.100779"]}}