{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Josa-Laorden C"],"funding":["Instituto de Salud Carlos III","European Union","Instituto de Salud Carlos III (ISCIII)"],"pagination":["3741-3749"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12450796"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(5)"],"pubmed_abstract":["<h4>Aims</h4>Effective decongestion is crucial in managing acute decompensated heart failure (ADHF). Persistent congestion post-diuretic therapy correlates with adverse outcomes. This study evaluates whether a strategy guided by intra-abdominal pressure (IAP) and point-of-care ultrasound (POCUS) enhances decongestion compared to standard diuretic titration.<h4>Methods and results</h4>ABDOPOCUS-HF is a randomized, multicentre, open-label, pragmatic clinical trial involving 168 patients hospitalized with ADHF across 14 Spanish hospitals. Inclusion criteria encompass clinical signs of congestion and elevated natriuretic peptides (NT-proBNP >1000 pg/mL or BNP > 250 pg/mL). Participants are randomized 1:1 to either standard care or an intervention arm where diuretic therapy is guided by baselin"],"journal":["ESC heart failure"],"pubmed_title":["The role of intra-abdominal pressure and point of care ultrasound to guide decongestive therapies in acute heart failure."],"pmcid":["PMC12450796"],"funding_grant_id":["PI23/00797"],"pubmed_authors":["Garcia-Lorente N","Torres-Macho J","Trullas JC","Salamanca-Bautista P","Fernandez-Villa N","Josa-Laorden C","Campos-Saenz de Santamaria A","Rubio-Gracia J","Torres-Courchoud I","Cobo-Marcos M","Pinilla MJ","Martinez-Gutierrez R","Serrano-Irigoyen P","Perez-Silvestre J","Mendez-Bailon M","Llacer-Iborra P","Morales-Rull JL","Sanchez-Marteles M","Montero-Hernandez E","Vazquez-Ronda MA","Crespo-Aznarez S"],"additional_accession":[]},"is_claimable":false,"name":"The role of intra-abdominal pressure and point of care ultrasound to guide decongestive therapies in acute heart failure.","description":"<h4>Aims</h4>Effective decongestion is crucial in managing acute decompensated heart failure (ADHF). Persistent congestion post-diuretic therapy correlates with adverse outcomes. This study evaluates whether a strategy guided by intra-abdominal pressure (IAP) and point-of-care ultrasound (POCUS) enhances decongestion compared to standard diuretic titration.<h4>Methods and results</h4>ABDOPOCUS-HF is a randomized, multicentre, open-label, pragmatic clinical trial involving 168 patients hospitalized with ADHF across 14 Spanish hospitals. Inclusion criteria encompass clinical signs of congestion and elevated natriuretic peptides (NT-proBNP >1000 pg/mL or BNP > 250 pg/mL). Participants are randomized 1:1 to either standard care or an intervention arm where diuretic therapy is guided by baselin","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-03T17:30:08.922Z","creation":"2026-04-30T03:07:16.305Z"},"accession":"S-EPMC12450796","cross_references":{"pubmed":["40739778"],"doi":["10.1002/ehf2.15380"]}}