{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Wang L"],"pubmed_abstract":["<h4>Objectives</h4>Atrial fibrillation/flutter (AF/AFL) is increasingly correlated with metabolic risk factors. This study analyzed mortality, disability-adjusted life years (DALYs), annual percentage changes (APCs), and estimated annual percentage changes (EAPCs), stratified by age, sex, Socio-demographic Index (SDI), and region, to evaluate the global burden of AF/AFL linked to metabolic risk factors.<h4>Methods</h4>Data on prevalence, incidence, mortality, DALYs, and age-standardized rates (ASRs) for AF/AFL associated with metabolic risk factors were extracted from the Global Burden of Disease (GBD) 2021 study. EAPCs were used to assess temporal trends in ASRs.<h4>Results</h4>In 2021, metabolic risk factors were correlated with approximately 117,012 deaths and 2,881,800 DALYs globally d"],"journal":["Frontiers in cardiovascular medicine"],"pagination":["1578908"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12450952"],"repository":["biostudies-literature"],"pubmed_title":["Global, regional, and national burden of atrial fibrillation and flutter associated with metabolic risk factors, 1990-2021."],"pmcid":["PMC12450952"],"pubmed_authors":["Qin X","Liu P","Wang H","Gong H","Gao C","Wang L","Jin L"],"additional_accession":[]},"is_claimable":false,"name":"Global, regional, and national burden of atrial fibrillation and flutter associated with metabolic risk factors, 1990-2021.","description":"<h4>Objectives</h4>Atrial fibrillation/flutter (AF/AFL) is increasingly correlated with metabolic risk factors. This study analyzed mortality, disability-adjusted life years (DALYs), annual percentage changes (APCs), and estimated annual percentage changes (EAPCs), stratified by age, sex, Socio-demographic Index (SDI), and region, to evaluate the global burden of AF/AFL linked to metabolic risk factors.<h4>Methods</h4>Data on prevalence, incidence, mortality, DALYs, and age-standardized rates (ASRs) for AF/AFL associated with metabolic risk factors were extracted from the Global Burden of Disease (GBD) 2021 study. EAPCs were used to assess temporal trends in ASRs.<h4>Results</h4>In 2021, metabolic risk factors were correlated with approximately 117,012 deaths and 2,881,800 DALYs globally d","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-06-03T18:48:34.808Z","creation":"2026-04-30T03:11:18.105Z"},"accession":"S-EPMC12450952","cross_references":{"pubmed":["40989114"],"doi":["10.3389/fcvm.2025.1578908"]}}