biostudies-literatureUnknown20(12)Laterza FPersistent descending mesocolon is a congenital anomaly in which the mesentery of the descending colon fails to fuse with the retroperitoneum, resulting in a mobile colon that is suspended by a mesentery extending from the left upper quadrant to the pelvic brim. This can predispose to intestinal obstruction by twisting of the colon, internal hernia with or without a mesenteric defect or intussusception. We present a case report of a 30-year-old male who presented with recurrent abdominal pain and distension, with a CT diagnosis of descending colonic volvulus due to persistent left mesocolon. The patient underwent a successful resection of the affected colon and had an uneventful recovery. This case highlights the importance of considering anatomical variants in the diagnosis and managementRadiology case reports5881-5885https://www.ebi.ac.uk/biostudies/studies/S-EPMC12454993biostudies-literatureDescending colon volvulus in a patient with persistent left mesocolon: A case report.PMC12454993Calbi RDattoli RCofone FDezio MLaterza FDiego MDCalabrese ACeccherini ADe Lucia DfalseDescending colon volvulus in a patient with persistent left mesocolon: A case report.Persistent descending mesocolon is a congenital anomaly in which the mesentery of the descending colon fails to fuse with the retroperitoneum, resulting in a mobile colon that is suspended by a mesentery extending from the left upper quadrant to the pelvic brim. This can predispose to intestinal obstruction by twisting of the colon, internal hernia with or without a mesenteric defect or intussusception. We present a case report of a 30-year-old male who presented with recurrent abdominal pain and distension, with a CT diagnosis of descending colonic volvulus due to persistent left mesocolon. The patient underwent a successful resection of the affected colon and had an uneventful recovery. This case highlights the importance of considering anatomical variants in the diagnosis and management2025-01-01T00:00:00Z2025 Dec2026-04-30T03:20:53.729Z2026-04-30T03:12:05.614ZS-EPMC124549934099473510.1016/j.radcr.2025.08.020