{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Blessinger KS"],"funding":["National Institute of Arthritis and Musculoskeletal and Skin Diseases","NIAMS NIH HHS"],"pagination":["2474-2488"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12457571"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["53(10)"],"pubmed_abstract":["Sit-to-stand (STS) transfer is essential for independent living and mobility in daily life but challenging for individuals before and after total knee arthroplasty (TKA). It remains unclear whether deficits in individual muscle function contribute to the lack of improvement in STS performance following TKA. The objective of this study was to determine whether lower extremity kinematics, muscle function during STS (quantified by muscle forces and muscle contributions to acceleration), and knee extension strength change following TKA. Dynamic musculoskeletal simulations of STS were performed for seven individuals before and six months after surgery. Computed muscle control and induced acceleration analysis were used to determine individual muscle forces and contributions to center of mass ac"],"journal":["Annals of biomedical engineering"],"pubmed_title":["Do Kinematics or Muscle Function During Sit-to-Stand Change Following a Primary Total Knee Arthroplasty?"],"pmcid":["PMC12457571"],"funding_grant_id":["R01AR056700"],"pubmed_authors":["Siston RA","Chaudhari AMW","Blessinger KS","Roelker SA","Lloyd RA","Schmitt LC"],"additional_accession":[]},"is_claimable":false,"name":"Do Kinematics or Muscle Function During Sit-to-Stand Change Following a Primary Total Knee Arthroplasty?","description":"Sit-to-stand (STS) transfer is essential for independent living and mobility in daily life but challenging for individuals before and after total knee arthroplasty (TKA). It remains unclear whether deficits in individual muscle function contribute to the lack of improvement in STS performance following TKA. The objective of this study was to determine whether lower extremity kinematics, muscle function during STS (quantified by muscle forces and muscle contributions to acceleration), and knee extension strength change following TKA. Dynamic musculoskeletal simulations of STS were performed for seven individuals before and six months after surgery. Computed muscle control and induced acceleration analysis were used to determine individual muscle forces and contributions to center of mass ac","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-03T18:49:43.81Z","creation":"2026-04-30T03:11:38.618Z"},"accession":"S-EPMC12457571","cross_references":{"pubmed":["40691751"],"doi":["10.1007/s10439-025-03782-3"]}}