{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["21(9)"],"submitter":["Kivisild A"],"pubmed_abstract":["<h4>Introduction</h4>We aimed to investigate early differences in sociodemographic factors before the onset of Alzheimer's disease (AD), frontotemporal dementia (FTD), vascular dementia (VaD), and mixed dementia (AD + VaD).<h4>Methods</h4>Lifetime sociodemographic factors were collected from Statistics Finland for 1238 AD, 274 FTD, 343 VaD, and 402 AD + VaD patients with a diagnosis and visit at Kuopio and Oulu University Hospitals between January 2010 and December 2021. Comparisons were performed between dementia groups and matched controls.<h4>Results</h4>All patient groups showed decreased employment status compared to controls already 10 years prior to diagnosis. In particular, individuals with early-onset FTD (EOFTD; 66.9% vs. 77.6%, p < 0.01) and early-onset VaD (EOVaD; 49.0% vs. 76."],"journal":["Alzheimer's & dementia : the journal of the Alzheimer's Association"],"pagination":["e70616"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12457979"],"repository":["biostudies-literature"],"pubmed_title":["Sociodemographic traits as early indicators of AD, FTD, and VaD up to 10 years before diagnosis."],"pmcid":["PMC12457979"],"pubmed_authors":["Solje E","Kivisild A","Soppela H","Lehtonen A","Tervonen L","Heikkinen S","Aaltonen M","Haapasalo A","Kruger J","Rinnankoski I","Katisko K","Ervasti K","Leppanen L","Aho K","Hartikainen P"],"additional_accession":[]},"is_claimable":false,"name":"Sociodemographic traits as early indicators of AD, FTD, and VaD up to 10 years before diagnosis.","description":"<h4>Introduction</h4>We aimed to investigate early differences in sociodemographic factors before the onset of Alzheimer's disease (AD), frontotemporal dementia (FTD), vascular dementia (VaD), and mixed dementia (AD + VaD).<h4>Methods</h4>Lifetime sociodemographic factors were collected from Statistics Finland for 1238 AD, 274 FTD, 343 VaD, and 402 AD + VaD patients with a diagnosis and visit at Kuopio and Oulu University Hospitals between January 2010 and December 2021. Comparisons were performed between dementia groups and matched controls.<h4>Results</h4>All patient groups showed decreased employment status compared to controls already 10 years prior to diagnosis. In particular, individuals with early-onset FTD (EOFTD; 66.9% vs. 77.6%, p < 0.01) and early-onset VaD (EOVaD; 49.0% vs. 76.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-03T19:36:23.163Z","creation":"2026-04-30T03:12:23.454Z"},"accession":"S-EPMC12457979","cross_references":{"pubmed":["40990183"],"doi":["10.1002/alz.70616"]}}