{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Kircher BK"],"funding":["NICHD NIH HHS","European Research Council","NCI NIH HHS"],"pubmed_abstract":["<h4>Background</h4>The brown anole is a model species of the genus <i>Anolis</i>, a squamate (encompassing lizards and snakes) group widely studied in evolutionary, behavioral, and developmental biology. Full genome annotation, the establishment of gene editing techniques, and comprehensive description of reproductive tract morphology and embryogenesis in this species, has laid the foundation for functional studies. However, analysis of brown anole oogenesis is still required and vital to optimize genome modification, mutant line establishment, and analyses of the evolution of reproductive developmental mechanisms.<h4>Results</h4>Here, we characterize ovary morphology and gametogenesis in the female brown anole, <i>A. sagrei</i> using brightfield imaging, microCT, histology staining, elect"],"journal":["bioRxiv : the preprint server for biology"],"pagination":["2025.09.11.675729"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12458429"],"repository":["biostudies-literature"],"pubmed_title":["Oogenesis and germinal bed morphology of the brown anole (&lt;i&gt;A. sagrei&lt;/i&gt;)."],"pmcid":["PMC12458429"],"funding_grant_id":["R37 HD030284","P30 CA016672","R01 HD030284","695669","R00 HD114881","R01 HD113569","K99 HD114881","T32 HD098068"],"pubmed_authors":["Williams SA","Kircher BK","Shylo NA","Starr K","Wilson H","McClain M","Weberling A","Griffin ZB","Hollfelder F","Sanger TJ","Vance EJ","Behringer RR","Trainor PA"],"additional_accession":[]},"is_claimable":false,"name":"Oogenesis and germinal bed morphology of the brown anole (&lt;i&gt;A. sagrei&lt;/i&gt;).","description":"<h4>Background</h4>The brown anole is a model species of the genus <i>Anolis</i>, a squamate (encompassing lizards and snakes) group widely studied in evolutionary, behavioral, and developmental biology. Full genome annotation, the establishment of gene editing techniques, and comprehensive description of reproductive tract morphology and embryogenesis in this species, has laid the foundation for functional studies. However, analysis of brown anole oogenesis is still required and vital to optimize genome modification, mutant line establishment, and analyses of the evolution of reproductive developmental mechanisms.<h4>Results</h4>Here, we characterize ovary morphology and gametogenesis in the female brown anole, <i>A. sagrei</i> using brightfield imaging, microCT, histology staining, elect","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-05-05T03:21:01.221Z","creation":"2026-05-05T03:13:14.243Z"},"accession":"S-EPMC12458429","cross_references":{"pubmed":["41000714"],"doi":["10.1101/2025.09.11.675729"]}}