{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(2)"],"submitter":["D'Ascenzo F"],"pubmed_abstract":["<h4>Introduction</h4>An evidence-based selection between fractional flow reserve (FFR) and optical coherence tomography (OCT) to drive percutaneous coronary intervention is still lacking.<h4>Methods</h4>Patients enrolled in the Fractional Flow Reserve vs. Optical Coherence Tomography to Guide Revascularization of Intermediate Coronary Stenoses (FORZA) trial and in the OCT-Features Of moRphology, coMposItion anD instABility of culprit and not culprit coronary pLaquE in ACS patient (OCT-FORMIDABLE) registry were included. Target vessel revascularisation (TVR) and major adverse cardiac events (MACE), a composite endpoint of cardiac death, myocardial infarction (MI) and TVR were considered as coprimary endpoints. Phenomapping with clustering was performed: incidence of outcomes according to FF"],"journal":["Open heart"],"pagination":["e003453"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12458727"],"repository":["biostudies-literature"],"pubmed_title":["Phenomapping-derived selection of fractional flow reserve or optical coherence tomography to personalise percutaneous coronary intervention."],"pmcid":["PMC12458727"],"pubmed_authors":["Capodanno D","Sanavia T","Bruno F","Burzotta F","Giacobbe F","Boccuzzi G","De Filippo O","Fariselli P","Leone AM","Iannaccone M","Souteyrand G","Sandrone S","Borzillo I","D'Ascenzo F","Amabile N","Caranzano I","De Ferrari GM","Ugo F","Aurigemma C","Ravetti E","Trani C"],"additional_accession":[]},"is_claimable":false,"name":"Phenomapping-derived selection of fractional flow reserve or optical coherence tomography to personalise percutaneous coronary intervention.","description":"<h4>Introduction</h4>An evidence-based selection between fractional flow reserve (FFR) and optical coherence tomography (OCT) to drive percutaneous coronary intervention is still lacking.<h4>Methods</h4>Patients enrolled in the Fractional Flow Reserve vs. Optical Coherence Tomography to Guide Revascularization of Intermediate Coronary Stenoses (FORZA) trial and in the OCT-Features Of moRphology, coMposItion anD instABility of culprit and not culprit coronary pLaquE in ACS patient (OCT-FORMIDABLE) registry were included. Target vessel revascularisation (TVR) and major adverse cardiac events (MACE), a composite endpoint of cardiac death, myocardial infarction (MI) and TVR were considered as coprimary endpoints. Phenomapping with clustering was performed: incidence of outcomes according to FF","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-03T19:49:37.664Z","creation":"2026-05-01T03:10:41.626Z"},"accession":"S-EPMC12458727","cross_references":{"pubmed":["40967674"],"doi":["10.1136/openhrt-2025-003453"]}}