biostudies-literatureUnknown13Deng Q<h4>Background</h4>Infertility represents a major global public health challenge. Identifying modifiable factors to optimize the outcomes of assisted reproductive technology (ART) is therefore crucial. Seasonal exposure has been reported to be correlated with natural conception rates, birth patterns, and adverse pregnancy outcomes. However, the potential associations between seasonal exposure and pregnancy outcomes among women undergoing fresh embryo transfer cycles remain controversial. This study aims to determine whether an association exists between seasonal exposure and pregnancy outcomes following fresh embryo transfer cycles, thereby providing evidence-based guidance on whether seasonal considerations should be integrated into ART treatment planning.<h4>Methods</h4>This review adherFrontiers in public health1660982https://www.ebi.ac.uk/biostudies/studies/S-EPMC12460414biostudies-literatureAssociation between season and pregnancy outcomes in fresh embryo transfer cycles: a systematic review and meta-analysis.PMC12460414Deng SHuang JZhu YDeng QWu FWang JYin LLi LJin ZYe ZfalseAssociation between season and pregnancy outcomes in fresh embryo transfer cycles: a systematic review and meta-analysis.<h4>Background</h4>Infertility represents a major global public health challenge. Identifying modifiable factors to optimize the outcomes of assisted reproductive technology (ART) is therefore crucial. Seasonal exposure has been reported to be correlated with natural conception rates, birth patterns, and adverse pregnancy outcomes. However, the potential associations between seasonal exposure and pregnancy outcomes among women undergoing fresh embryo transfer cycles remain controversial. This study aims to determine whether an association exists between seasonal exposure and pregnancy outcomes following fresh embryo transfer cycles, thereby providing evidence-based guidance on whether seasonal considerations should be integrated into ART treatment planning.<h4>Methods</h4>This review adher2025-01-01T00:00:00Z20252026-06-06T13:37:37.893Z2026-05-31T03:07:57.886ZS-EPMC124604144101878010.3389/fpubh.2025.1660982