{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Monari C"],"funding":["PRIN: PROGETTI DI RICERCA DI RILEVANTE INTERESSE NAZIONALE- Bando 2022 PNRR, Ministero dell'Università, project \"Analysis of resistome and virulome among carbapenem-resistant Gram-negative bacteria and their correlation with clinical and microbiological outcomes in a cohort of hospitalized patients with colonization or infection: a multicentre prospective study\""],"pagination":["2061-2072"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12460482"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["53(5)"],"pubmed_abstract":["<h4>Introduction</h4>In accordance with the spread of drug-resistant bacteria worldwide, an increase in the prevalence of Antimicrobial Resistance (AMR) among pathogens causing urinary tract infections (UTIs) has been described globally. The aim of this study was to describe the prevalence and outcome of UTIs caused by third-generation cephalosporin-resistant (3GC-R) Enterobacterales in a prospective cohort of patients admitted to Emergency Department (ED).<h4>Materials and methods</h4>We conducted an observational prospective multicentre study, involving 7 healthcare facilities, enrolling all consecutive adult patients admitted to ED with a microbiologically confirmed diagnosis of UTIs caused by Enterobacterales. The primary outcomes were the prevalence of UTIs caused by 3GC-R Enterobacte"],"journal":["Infection"],"pubmed_title":["Prevalence and outcomes of Urinary tract infections caused by Enterobacterales resistant to third-generation cephalosporins in the Emergency Department: results from UTILY cohort, a prospective multicentre study."],"pmcid":["PMC12460482"],"funding_grant_id":["1111"],"pubmed_authors":["Numis FG","Iula VD","Russo K","Palo V","Di Sisto A","Schettini F","Raucci R","De Luca I","Giordano M","Macera M","Allegretto A","Quaranta N","Amelia A","Mari F","Fabozzi F","De Capua L","Ferraro A","Carozza L","Palumbo A","Palumbo F","Onorato L","Migliaccio B","Salvati A","Florio MT","Viola S","Morelli R","Miglietta F","Monari C","Finelli M","Dello Vicario F","Serrao V","Vespoli I","Allegorico E","Bianco P","Perez Guillen E","Augiero A","Nasti R","Esposito F","Cornelli A","Borrelli G","Brunelli V","Delle Femmine A","Sciorio R","Santagata A","Nasta C","for UTILY study group*","Pomilla G","Guesmi D","Ciminelli F","Amato A","Coppola N","Facciuto AI","Voza A","Rocco M","Crispino N","Guida I","Guiotto G","Mariniello A","Aiello S"],"additional_accession":[]},"is_claimable":false,"name":"Prevalence and outcomes of Urinary tract infections caused by Enterobacterales resistant to third-generation cephalosporins in the Emergency Department: results from UTILY cohort, a prospective multicentre study.","description":"<h4>Introduction</h4>In accordance with the spread of drug-resistant bacteria worldwide, an increase in the prevalence of Antimicrobial Resistance (AMR) among pathogens causing urinary tract infections (UTIs) has been described globally. The aim of this study was to describe the prevalence and outcome of UTIs caused by third-generation cephalosporin-resistant (3GC-R) Enterobacterales in a prospective cohort of patients admitted to Emergency Department (ED).<h4>Materials and methods</h4>We conducted an observational prospective multicentre study, involving 7 healthcare facilities, enrolling all consecutive adult patients admitted to ED with a microbiologically confirmed diagnosis of UTIs caused by Enterobacterales. The primary outcomes were the prevalence of UTIs caused by 3GC-R Enterobacte","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-03T19:51:36.329Z","creation":"2026-05-01T03:10:56.834Z"},"accession":"S-EPMC12460482","cross_references":{"pubmed":["40343569"],"doi":["10.1007/s15010-025-02547-3"]}}