biostudies-literatureUnknown53(5)Teixeira-Antunes AUniversity of Lausanne<h4>Purpose</h4>To ascertain the predictors of persistent bacteraemia among patients with suspected infective endocarditis (IE) and those with IE.<h4>Methods</h4>Retrospective study.<h4>Setting</h4>This study conducted at a Swiss university hospital (2015-2023) included adult patients with bacteraemia and suspected IE. Persistent bacteraemia was defined as continued positive blood cultures with the same microorganism for at least 48 h from antibiotic treatment initiation. Endocarditis Team classified cases as IE or not IE.<h4>Results</h4>Among 2312 episodes of suspected IE, S. aureus was the most common pathogen (1045 episodes; 45%). IE (644; 28%) was the most prevalent infection type. Persistent bacteraemia was observed in 480 (21%) episodes and was independently associated with S. aureusInfection2015-2024https://www.ebi.ac.uk/biostudies/studies/S-EPMC12460498biostudies-literatureFactors associated with persistent bacteraemia among patients with suspected infective endocarditis.PMC12460498Teixeira-Antunes APapadimitriou-Olivgeris MKirsch MTzimas GGuery BZimmermann VMonney PSenn LTozzi PIanculescu NFourre NfalseFactors associated with persistent bacteraemia among patients with suspected infective endocarditis.<h4>Purpose</h4>To ascertain the predictors of persistent bacteraemia among patients with suspected infective endocarditis (IE) and those with IE.<h4>Methods</h4>Retrospective study.<h4>Setting</h4>This study conducted at a Swiss university hospital (2015-2023) included adult patients with bacteraemia and suspected IE. Persistent bacteraemia was defined as continued positive blood cultures with the same microorganism for at least 48 h from antibiotic treatment initiation. Endocarditis Team classified cases as IE or not IE.<h4>Results</h4>Among 2312 episodes of suspected IE, S. aureus was the most common pathogen (1045 episodes; 45%). IE (644; 28%) was the most prevalent infection type. Persistent bacteraemia was observed in 480 (21%) episodes and was independently associated with S. aureus2025-01-01T00:00:00Z2025 Oct2026-06-03T19:38:38.928Z2026-04-30T03:12:30.255ZS-EPMC124604984019295910.1007/s15010-025-02537-5