biostudies-literatureBrobbin ENIHR ARC South LondonMedical Research CouncilNational Institute for Health Research (NIHR)agad068https://www.ebi.ac.uk/biostudies/studies/S-EPMC12461868biostudies-literatureUnknown59(1)The development of transdermal alcohol sensors (TASs) presents a new method to monitor alcohol consumption with the ability to objectively measure data 24/7. We aimed to evaluate the accuracy of two TASs (BACtrack Skyn and Smart Start BARE) in a laboratory setting. Thirty-two adults received a dose of ethanol 0.56 g/kg body weight as a 20% solution while wearing the two TASs and provided Breath Alcohol Concentration (BrAC) measurements for 3.5 h postalcohol consumption. Pearson's correlations and repeated measures analysis of variance tests were conducted on the peak, time-to-peak, and area under the curve data. Bland-Altman plots were derived. A time series analysis and cross-correlations were conducted to adjust for time lag. Both TASs were able to detect alcohol and increase within 20 mAlcohol and alcoholism (Oxford, Oxfordshire)Accuracy of transdermal alcohol monitoring devices in a laboratory setting.PMC12461868RP-PG-0609-10162G0701818NF-SI-0616-10077NIHR202440NIHR200152NIHR-INF-145113/86/03Coulton SBrobbin EDeluca PDrummond CfalseAccuracy of transdermal alcohol monitoring devices in a laboratory setting.The development of transdermal alcohol sensors (TASs) presents a new method to monitor alcohol consumption with the ability to objectively measure data 24/7. We aimed to evaluate the accuracy of two TASs (BACtrack Skyn and Smart Start BARE) in a laboratory setting. Thirty-two adults received a dose of ethanol 0.56 g/kg body weight as a 20% solution while wearing the two TASs and provided Breath Alcohol Concentration (BrAC) measurements for 3.5 h postalcohol consumption. Pearson's correlations and repeated measures analysis of variance tests were conducted on the peak, time-to-peak, and area under the curve data. Bland-Altman plots were derived. A time series analysis and cross-correlations were conducted to adjust for time lag. Both TASs were able to detect alcohol and increase within 20 m2024-01-01T00:00:00Z2024 Jan2026-06-03T20:27:21.354Z2026-06-01T03:06:07.794ZS-EPMC124618683787396710.1093/alcalc/agad068