{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Teruya KI"],"funding":["Conselho Nacional de Desenvolvimento Científico e Tecnológico","Coordenação de Aperfeiçoamento de Pessoal de Nível Superior"],"pagination":["487"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12461978"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(1)"],"pubmed_abstract":["<h4>Background</h4>Metabolic control in the phenylketonuria (PKU) population is challenging. Perceived barriers to treatment adherence have been shown to be associated with metabolic control outcomes. The objective of this study was to evaluate the psychometric properties of the Perceived Barriers to PKU Treatment Inventory with patients and caregivers in different regions of Brazil.<h4>Methods</h4>This is a cross-sectional, observational, non-probability sampling study. The inventory has 25 dichotomous items and two versions, patients and caregivers. Data collection in the present study included online assessment (n = 241) and presential mode (n = 42). Sixty-three PKU patients and 220 caregivers of individuals with PKU participated in this study. Internal consistency reliability, converge"],"journal":["Orphanet journal of rare diseases"],"pubmed_title":["Psychometric properties of perceived barriers to PKU treatment inventory in a Brazilian national sample."],"pmcid":["PMC12461978"],"funding_grant_id":["001","313308/2021-7"],"pubmed_authors":["Teruya KI","Schwartz IVD","Remor E"],"additional_accession":[]},"is_claimable":false,"name":"Psychometric properties of perceived barriers to PKU treatment inventory in a Brazilian national sample.","description":"<h4>Background</h4>Metabolic control in the phenylketonuria (PKU) population is challenging. Perceived barriers to treatment adherence have been shown to be associated with metabolic control outcomes. The objective of this study was to evaluate the psychometric properties of the Perceived Barriers to PKU Treatment Inventory with patients and caregivers in different regions of Brazil.<h4>Methods</h4>This is a cross-sectional, observational, non-probability sampling study. The inventory has 25 dichotomous items and two versions, patients and caregivers. Data collection in the present study included online assessment (n = 241) and presential mode (n = 42). Sixty-three PKU patients and 220 caregivers of individuals with PKU participated in this study. Internal consistency reliability, converge","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-03T20:34:04.964Z","creation":"2026-05-01T03:11:08.972Z"},"accession":"S-EPMC12461978","cross_references":{"pubmed":["40993707"],"doi":["10.1186/s13023-025-03998-5"]}}