biostudies-literatureSiew RVKNational Health and Medical Research Council3068https://www.ebi.ac.uk/biostudies/studies/S-EPMC12461985biostudies-literatureUnknown25(1)<h4>Background</h4>The adoption of health-damaging lifestyle behaviours may be a coping mechanism stemming from maladaptive behavioural stress response to stress exposure, but little is known about the influence of stressors on health-damaging lifestyle behaviour clusters. This study aimed to identify clusters of lifestyle behaviours based on six lifestyle-related behaviours and to examine the associations between childhood adversity, stressful and traumatic life events, and the clusters of lifestyle behaviours in community-dwelling Australian adults.<h4>Methods</h4>This prospective study comprises 1773 adults aged 40-44 years at baseline from the Personality and Total Health (PATH) Through Life Study. Data on childhood adversity, stressful life events, traumatic life events were obtained BMC public healthProspective associations between stressful life course events and clusters of lifestyle behaviours.PMC12461985973302, 179805, 418139Leach LTurner AITorres SJCherbuin NHansen AMSiew RVKAbbott GButterworth PNilsson CJfalseProspective associations between stressful life course events and clusters of lifestyle behaviours.<h4>Background</h4>The adoption of health-damaging lifestyle behaviours may be a coping mechanism stemming from maladaptive behavioural stress response to stress exposure, but little is known about the influence of stressors on health-damaging lifestyle behaviour clusters. This study aimed to identify clusters of lifestyle behaviours based on six lifestyle-related behaviours and to examine the associations between childhood adversity, stressful and traumatic life events, and the clusters of lifestyle behaviours in community-dwelling Australian adults.<h4>Methods</h4>This prospective study comprises 1773 adults aged 40-44 years at baseline from the Personality and Total Health (PATH) Through Life Study. Data on childhood adversity, stressful life events, traumatic life events were obtained 2025-01-01T00:00:00Z2025 Sep2026-06-03T20:27:25.17Z2026-06-01T03:06:09.419ZS-EPMC124619854099361410.1186/s12889-025-24110-3