biostudies-literatureBravo ACGobierno Vasco-Eusko JaurlaritzaINTERCEPTCEREGA/Portuguese Gastroenterology Society and GENIUS-Luz Learning Health1226-1238https://www.ebi.ac.uk/biostudies/studies/S-EPMC12463702biostudies-literatureUnknown13(7)<h4>Background and objective</h4>While significant advances have been made in identifying biomarkers for predicting inflammatory bowel disease (IBD) onset, little is known about the willingness of at-risk individuals to undergo predictive testing and preventive interventions. This study aimed to assess acceptance of predictive tests and preventive interventions among individuals at risk of inflammatory bowel disease and identify factors influencing their decisions.<h4>Methods</h4>An anonymized electronic survey was distributed to parents of children at risk of inflammatory bowel disease and first-degree relatives (FDRs) of IBD patients via clinicians and patient associations. The survey assessed acceptance of predictive tests, preventive interventions, and influencing variables.<h4>ResultsUnited European gastroenterology journalPatient and First-Degree Relatives Perceptions About Prediction and Prevention of Inflammatory Bowel Disease-A Multinational Survey.PMC1246370210119478020232220062020111061Ribas AStemmer NUngaro RJuillerat PColombel JFTorres JIzquierdo VPPeter IJulsgaard MBravo ACSorensen HGMorao BFiorino GLeone SCroitoiru KSpencer EAGinard DChristensen SGQueiroz NBuisson AMoss AAvedano LRodriguez-Lago IAgrawal MSiegel CAExposito LFidalgo CfalsePatient and First-Degree Relatives Perceptions About Prediction and Prevention of Inflammatory Bowel Disease-A Multinational Survey.<h4>Background and objective</h4>While significant advances have been made in identifying biomarkers for predicting inflammatory bowel disease (IBD) onset, little is known about the willingness of at-risk individuals to undergo predictive testing and preventive interventions. This study aimed to assess acceptance of predictive tests and preventive interventions among individuals at risk of inflammatory bowel disease and identify factors influencing their decisions.<h4>Methods</h4>An anonymized electronic survey was distributed to parents of children at risk of inflammatory bowel disease and first-degree relatives (FDRs) of IBD patients via clinicians and patient associations. The survey assessed acceptance of predictive tests, preventive interventions, and influencing variables.<h4>Results2025-01-01T00:00:00Z2025 Sep2026-06-03T21:06:24.047Z2026-05-30T03:07:17.514ZS-EPMC124637024082775810.1002/ueg2.70091