{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Yang B"],"pubmed_abstract":["<h4>Background</h4>To bridge the gap between clinical guidelines and suboptimal stroke management in rural settings, we conducted an implementation trial using evidence-based, mobile health-enabled strategies to empower primary care providers in rural China. The system-integrated and digital technology-enabled model of care (SINEMA) model was shown to significantly reduce blood pressure and mortality among people with stroke in rural China.<h4>Objective</h4>This study aimed to evaluate the cost-effectiveness of the SINEMA intervention within both the active trial and the post-trial observational periods and its budget impact for potential nationwide scalability.<h4>Methods</h4>In the cluster-randomized implementation trial (the SINEMA trial), 50 villages were randomized to either a 1-year "],"journal":["JMIR mHealth and uHealth"],"pagination":["e75326"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12464504"],"repository":["biostudies-literature"],"pubmed_title":["Economic Evaluation of a Multicomponent mHealth Intervention for Stroke Management in Rural China: Cluster-Randomized Trial With 6-Year Follow-Up."],"pmcid":["PMC12464504"],"pubmed_authors":["Finkelstein E","Si L","Tan J","Cai J","Yang B","Chen C","Gong E","Dong D","Li Y","Yan LL","Oldenburg B","Zhang X","Chen X","Peoples N"],"additional_accession":[]},"is_claimable":false,"name":"Economic Evaluation of a Multicomponent mHealth Intervention for Stroke Management in Rural China: Cluster-Randomized Trial With 6-Year Follow-Up.","description":"<h4>Background</h4>To bridge the gap between clinical guidelines and suboptimal stroke management in rural settings, we conducted an implementation trial using evidence-based, mobile health-enabled strategies to empower primary care providers in rural China. The system-integrated and digital technology-enabled model of care (SINEMA) model was shown to significantly reduce blood pressure and mortality among people with stroke in rural China.<h4>Objective</h4>This study aimed to evaluate the cost-effectiveness of the SINEMA intervention within both the active trial and the post-trial observational periods and its budget impact for potential nationwide scalability.<h4>Methods</h4>In the cluster-randomized implementation trial (the SINEMA trial), 50 villages were randomized to either a 1-year ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-03T21:21:41.786Z","creation":"2026-05-01T03:10:55.427Z"},"accession":"S-EPMC12464504","cross_references":{"pubmed":["40934495"],"doi":["10.2196/75326"]}}