{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jiao Y"],"funding":["fengyang wang"],"pagination":["2702"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12466515"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(18)"],"pubmed_abstract":["The Xinglong buffalo is a local swamp buffalo breed adapted to tropical regions in China. To facilitate the protection and utilization of valuable genetic resources, we first developed the breed-specific single nucleotide polymorphism (SNP) liquid-phase chip based on genotyping-by-target-sequencing (GBTS) technology. Whole-genome resequencing data from 143 buffaloes, resulting in 34,757,694 SNPs, were used to identify 1208 breed-specific and 2889 background sites. This chip also incorporates 965 functional SNP sites derived from literature, including SNPs significantly associated with immunity, reproduction, growth, and production. A total of 5062 SNP sites were successfully identified for the development of a 5K liquid-phase genome-wide breeding chip for the Xinglong buffalo. The validati"],"journal":["Animals : an open access journal from MDPI"],"pubmed_title":["Development of a 5K Liquid-Phase Genome-Wide Breeding Chip for Xinglong Buffalo."],"pmcid":["PMC12466515"],"funding_grant_id":["[2025]100"],"pubmed_authors":["Jiang J","Chen Q","Cui K","Wang F","Gao H","Li L","Qiu X","Li S","Man C","Li B","Chen S","Jiao Y","Du L","Chen T"],"additional_accession":[]},"is_claimable":false,"name":"Development of a 5K Liquid-Phase Genome-Wide Breeding Chip for Xinglong Buffalo.","description":"The Xinglong buffalo is a local swamp buffalo breed adapted to tropical regions in China. To facilitate the protection and utilization of valuable genetic resources, we first developed the breed-specific single nucleotide polymorphism (SNP) liquid-phase chip based on genotyping-by-target-sequencing (GBTS) technology. Whole-genome resequencing data from 143 buffaloes, resulting in 34,757,694 SNPs, were used to identify 1208 breed-specific and 2889 background sites. This chip also incorporates 965 functional SNP sites derived from literature, including SNPs significantly associated with immunity, reproduction, growth, and production. A total of 5062 SNP sites were successfully identified for the development of a 5K liquid-phase genome-wide breeding chip for the Xinglong buffalo. The validati","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-05-02T03:18:45.492Z","creation":"2026-05-02T03:11:49.667Z"},"accession":"S-EPMC12466515","cross_references":{"pubmed":["41007947"],"doi":["10.3390/ani15182702"]}}