biostudies-literatureOkada SJapan Association for Livestock New Technology2638https://www.ebi.ac.uk/biostudies/studies/S-EPMC12466595biostudies-literatureUnknown15(18)Oxidative stress is a detrimental factor affecting pig reproductive performance but has rarely been evaluated in clinical fields. We evaluated the potential of diacron-reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP) as stable markers for assessing oxidative stress in breeding sows. The 28 sows were categorized into a low-parity group (n = 18, parity 1-2) and a high-parity group (n = 10, parity 4-6) at two commercial farms. Blood samples were collected at three stages: farrowing, weaning, and early pregnancy. At each stage, the levels of oxidative stress markers and reproductive performance parameters were statistically analyzed. The findings revealed that heightened levels of oxidative stress in sows at farrowing have negative effects on the total number of Animals : an open access journal from MDPIVariations in Diacron-Reactive Oxygen Metabolites and Biological Antioxidant Potential Across Reproductive Phases and Parities in Sows Reared Under Different Production Systems.PMC12466595No dataSato RSasaki YNoguchi MOkada SfalseVariations in Diacron-Reactive Oxygen Metabolites and Biological Antioxidant Potential Across Reproductive Phases and Parities in Sows Reared Under Different Production Systems.Oxidative stress is a detrimental factor affecting pig reproductive performance but has rarely been evaluated in clinical fields. We evaluated the potential of diacron-reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP) as stable markers for assessing oxidative stress in breeding sows. The 28 sows were categorized into a low-parity group (n = 18, parity 1-2) and a high-parity group (n = 10, parity 4-6) at two commercial farms. Blood samples were collected at three stages: farrowing, weaning, and early pregnancy. At each stage, the levels of oxidative stress markers and reproductive performance parameters were statistically analyzed. The findings revealed that heightened levels of oxidative stress in sows at farrowing have negative effects on the total number of 2025-01-01T00:00:00Z2025 Sep2026-05-02T03:14:12.922Z2026-05-02T03:08:01.154ZS-EPMC124665954100788410.3390/ani15182638