biostudies-literatureZhou Ythe Major Science and Technology Special Project of the Xinjiang Uygur Autonomous Regionthe 2025 Central Guidance for Local Science and Technology Development Funding Project "Research on Breeding and Exercise Performance Regulation Mechanisms in Horses"1285https://www.ebi.ac.uk/biostudies/studies/S-EPMC12467213biostudies-literatureUnknown14(9)The Kazakh horse is a highly valuable indigenous Chinese breed known for its use in both milk and meat production. However, the mechanisms underlying color variation in the abdominal adipose tissue of this breed remain poorly understood. In this study, the sequencing of non-coding RNAs (ncRNAs) was conducted on abdominal adipose tissue of different colors from Kazakh horses, with the aim of investigating the molecular mechanisms responsible for this variation. A total of 205 differentially expressed long non-coding RNAs (DELncRNAs) including <i>ENSECAG00000003836</i>, <i>ENSECAG00000017858</i>, and <i>ENSECAG00000035167</i>; 52 differentially expressed microRNAs (DEmiRNAs) including <i>miR-200-y</i> and <i>eca-miR-9a</i>; and 559 differentially expressed circular RNAs (DEcircRNAs) includinBiologyMechanisms of Variation in Abdominal Adipose Color Among Male Kazakh Horses Through Non-Coding RNA Sequencing.PMC12467213ZYYD2025JD022022A02013-1Ren WZeng YZhou YYao XMeng JWang JLi LfalseMechanisms of Variation in Abdominal Adipose Color Among Male Kazakh Horses Through Non-Coding RNA Sequencing.The Kazakh horse is a highly valuable indigenous Chinese breed known for its use in both milk and meat production. However, the mechanisms underlying color variation in the abdominal adipose tissue of this breed remain poorly understood. In this study, the sequencing of non-coding RNAs (ncRNAs) was conducted on abdominal adipose tissue of different colors from Kazakh horses, with the aim of investigating the molecular mechanisms responsible for this variation. A total of 205 differentially expressed long non-coding RNAs (DELncRNAs) including <i>ENSECAG00000003836</i>, <i>ENSECAG00000017858</i>, and <i>ENSECAG00000035167</i>; 52 differentially expressed microRNAs (DEmiRNAs) including <i>miR-200-y</i> and <i>eca-miR-9a</i>; and 559 differentially expressed circular RNAs (DEcircRNAs) includin2025-01-01T00:00:00Z2025 Sep2026-05-02T03:10:42.617Z2026-05-02T03:07:43.782ZS-EPMC124672134100742910.3390/biology14091285